Evidence map›Paper›PMID 42205645›Full record

ArticleCureus2026

Utilizing Apple Vision Pro for Mindfulness Intervention to Reduce Pain and Anxiety in a Hospitalized Patient With Mixed Connective Tissue Disease: A Case Report.

Pouya Azar, James Wong, Mohammadali Nikoo, Victor W Li, Jessica Machado, Tam To, Christopher Haslam, Rodney Mullen, Borna Noureddin

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pouya AzarPsychiatry, Vancouver General Hospital, Vancouver, CAN.
James WongPsychiatry, Vancouver General Hospital, Vancouver, CAN.
Mohammadali NikooPsychiatry, Vancouver General Hospital, Vancouver, CAN.
Victor W LiPsychiatry, University of British Columbia, Faculty of Medicine, Vancouver, CAN.
Jessica MachadoPsychiatry, Vancouver General Hospital, Vancouver, CAN.
Tam ToPsychiatry, University of British Columbia, Faculty of Medicine, Vancouver, CAN.
Christopher HaslamPsychiatry, Vancouver General Hospital, Vancouver, CAN.
Rodney MullenPsychiatry, Vancouver General Hospital, Vancouver, CAN.
Borna NoureddinComputing, British Columbia Institute of Technology, Burnaby, CAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing and evaluating non-pharmacological treatments is critical for optimizing pain management and reducing dependence on opioids, as well as mitigating opioid-induced adverse effects. One promising approach involves the use of virtual reality (VR)- and augmented reality (AR)-guided mindfulness techniques. We examined the clinical utility of the Mindfulness app on the Apple Vision Pro VR/AR headset in managing pain and anxiety in a hospitalized patient with mixed connective tissue disease. This case study presents a 22-year-old woman experiencing progressive acute-on-chronic pain and weakness, significantly impairing her mobility due to mixed connective tissue disease. The case report evaluated the effectiveness of a built-in Mindfulness app provided through AR on the Vision Pro. Conducted over 48 hours, the study assessed pain, anxiety, and as-needed medication usage before, during, and after the intervention for a single subject. The patient participated in six intervention sessions, each averaging 59.67 minutes in duration. The Mindfulness app on the device reduced pain from an average of 4.67/10 pre-intervention to 1.83/10 post-intervention (p=0.03) and anxiety from an average of 6.5/10 pre-intervention to 2.83/10 post-intervention (p=0.03). The patient reported an overall positive experience with a motivation to utilize mindfulness interventions further in the future. The patient experienced some discomfort with the device due to its suboptimal fit and tolerable eye strain with prolonged use. Utilizing Apple Vision Pro to deliver mindfulness interventions could serve as a viable non-pharmacological treatment modality for pain. Further research with adequately powered larger sample sizes and controlled designs is recommended to further study such interventions.

Indexed as

anxietyaugmented realitycase reportopioidpainvirtual reality

Identifiers

PMID42205645
PMCPMC13211975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.