Evidence map›Paper›PMID 42205594›Full record

ArticleBMJ oncology2026

Inequalities in cancer diagnostic outcomes for patients with a learning disability: a retrospective cohort study in England.

Bianca Wiering, Gary A Abel, Leon Farmer, Robert Kerrison, Samuel W D Merriel, Sarah Price, David Shotter, Jose M Valderas, Luke T A Mounce

Abstract read
In one paragraph

Article in BMJ oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Yonder.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bianca WieringDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0001-6708-5705
Gary A AbelDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.
Leon FarmerDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.
Robert KerrisonUniversity of Surrey, Guildford, UK.
Samuel W D MerrielDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0003-2919-9087
Sarah PriceDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0002-2228-2374
David ShotterDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.
Jose M ValderasDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.ORCID https://orcid.org/0000-0002-9299-1555
Luke T A MounceDepartment of Health and Community Sciences, University of Exeter, Exeter, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The cancer diagnostic process may be more complicated for patients with a learning disability ('intellectual disability' outside of the UK) than for other patients. We aimed to investigate whether patients with a learning disability were more likely to experience disadvantage in cancer diagnostic pathways and outcomes. Design: A retrospective cohort study using routinely collected linked data across primary care and cancer registration. Setting: 1470 general practices in England. Participants: 277 050 participants who were aged 40+ years, had an incident cancer recorded in the cancer registration during 2012-2018 and were registered for at least 3 years at their general practice prior to diagnosis. Main outcome measures: Emergency presentation route to diagnosis or urgent suspected cancer referral route to diagnosis, cancer stage at diagnosis (early vs advanced) and all-cause mortality within 30 days after diagnosis. Results: 277 050 patients were included in the overall study, of which 211 423 were included in analyses with cancer stage as outcome. Learning disability was recorded for 796 (0.3%) patients. Patients with a learning disability were over twice as likely to be diagnosed via an emergency presentation (adjusted OR (aOR): 2.65, 95% CI 2.26 to 3.11, p<0.001) and half as likely to be diagnosed via an urgent suspected cancer referral (aOR: 0.51, 95% CI 0.43 to 0.60, p<0.001). They were also more likely to be diagnosed with advanced-stage cancer (aOR: 1.37, 95% CI 1.12 to 1.67, p=0.002), especially for breast cancer, and to die within 30 days of diagnosis (aOR: 3.77, 95% CI 3.10 to 4.59, p<0.001) than patients without a learning disability. Conclusions: Patients with a learning disability experience marked inequalities in cancer diagnostic pathways and outcomes. The increased risk of advanced-stage breast cancer is of particular note. Improved support to access and navigate the health care system may be required to negate experienced difficulties during the diagnostic process.

Indexed as

EpidemiologyHealth Services ResearchMortality

Identifiers

PMID42205594
PMCPMC13202048

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.