Evidence map›Paper›PMID 42205555›Full record

ArticleRSC advances2026

A rhein-integrated hydrogel dressing with antibacterial, antioxidant and pH-responsive colorimetric properties.

Miaoshen Kou, Deng Wang, Jiawei Zhang, Fangzheng Yu, Yang Yuan, Chen Wang, Jiale He, Zheng Zhao, Yichao Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miaoshen KouState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Deng WangRespiratory and Critical Care Medicine Department of Ezhou Central Hospital Ezhou City 436000 China.
Jiawei ZhangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Fangzheng YuState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Yang YuanState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Chen WangState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Jiale HeState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.
Zheng ZhaoState Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology Wuhan 430070 China zhengzhao@whut.edu.cn.ORCID https://orcid.org/0000-0002-0574-3095
Yichao LiuDepartment of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan University Wuhan 430071 China yichaoliu619@whu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrating bioactive function with wound-status indication remains a major challenge in the design of hydrogel dressings for complex wound management. Most pH-responsive hydrogels still rely on separate bioactive and sensing components, leading to increased compositional and fabrication complexity and highlighting the need for unified platforms based on a single bioactive molecule with intrinsic pH responsiveness. In this work, a multifunctional SF/HA/Rhe hydrogel dressing was developed by incorporating rhein (Rhe), a plant-derived small molecule, into a silk fibroin/hyaluronic acid (SF/HA) matrix. Rhe served as a single functional component that simultaneously endowed the hydrogel with antibacterial, antioxidant and pH-responsive colorimetric properties. The optimized SF/HA/Rhe hydrogel achieved antibacterial rates above 94% against

Identifiers

PMID42205555
PMCPMC13202421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.