Evidence map›Paper›PMID 42205471›Full record

ArticleCardiopulmonary physical therapy journal2025

Higher Heart Rates During Locomotor High-Intensity Interval Training Are Associated With Gait Asymmetry and Fatigue After Stroke.

Alicen A Whitaker-Hilbig, Pierce Boyne, Darcy S Reisman, Kiersten McCartney, Jacqueline A Palmer, Sergey Tarima, Sandra A Billinger

Abstract read
In one paragraph

Article in Cardiopulmonary physical therapy journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alicen A Whitaker-HilbigDepartment of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, WI.ORCID 0000-0002-8701-9227
Pierce BoyneDepartment of Rehabilitation, Exercise and Nutrition Sciences, College of Allied Health Sciences, University of Cincinnati, Cincinnati, OH.
Darcy S ReismanDepartment of Physical Therapy, University of Delaware, Newark, DE.
Kiersten McCartneyDepartment of Physical Therapy, University of Delaware, Newark, DE.
Jacqueline A PalmerDivision of Physical Therapy, University of Minnesota, Minneapolis, MN.
Sergey TarimaDivision of Biostatistics, Medical College of Wisconsin, Milwaukee, WI.
Sandra A BillingerDepartment of Neurology, University of Kansas Medical Center, Kansas City, KS.

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI MEINZEN-DERR, JAREEN, STRAWN, JEFFREY ROBERT · 2015 to 2024
$37.5M
University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI JEFFREY Murray BURNS · 2021 to 2026
$25.3M
High-Intensity Interval Training to Recover Walking Post-Stroke: HIT-Stroke Trial 2R01HD093694 · NICHD · UNIVERSITY OF CINCINNATI · PI Pierce Boyne · 2018 to 2026
$6.1M
Training in Signature Transdisciplinary Cardiovascular SciencesT32HL134643 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Justin L Grobe, Jacquelyn P Kulinski · 2017 to 2026
$4.2M
NRSA Training CoreTL1TR002368 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jennifer Lynn Goldman, NICOLE L NOLLEN · 2017 to 2026
$4.0M
PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
Kansas University Training Program in Neurological and Rehabilitation SciencesT32HD057850 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Jacob J. Sosnoff · 2009 to 2026
$3.4M
Investigating cerebrovascular regulation during exercise as a factor influencing cortical resource engagement for balance control with agingK99AG075255 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI PALMER, JACQUELINE A · 2022 to 2023
$234k
NCATS NIH HHS TL1 TR002368NCATS NIH HHS UL1 TR001425NHLBI NIH HHS T32 HL134643NIA NIH HHS K99 AG075255NIA NIH HHS P30 AG072973NICHD NIH HHS R01 HD093694NICHD NIH HHS T32 HD007490NICHD NIH HHS T32 HD057850
6 · The paper itself

Abstract

Purpose: Individuals poststroke with severe hemiparesis and deconditioning may have physical difficulty walking fast and/or long enough to perform vigorous cardiovascular intensity during locomotor high-intensity interval training (HIIT). We hypothesized that baseline walking function would be associated with the average percent heart rate reserve (%HRR) performed during locomotor HIIT. Methods: Baseline assessments included walking endurance (6-min walk test), comfortable and fast walking speed (10-m walk), step length and single-limb support symmetry (electronic walkway), and metabolic cost of fast walking (ml O Results: Twenty-seven individuals were allocated to HIIT (age 63 ± 10 years, 2.7 ± 1.4 years poststroke). Less baseline walking step length symmetry ( Conclusion: Few baseline walking characteristics were associated with cardiovascular intensity during the initiation of locomotor HIIT, potentially because of large variability in the heart rate response. As individuals progressed over time and were able to reach higher cardiovascular intensity, the associations were abrogated.

Indexed as

cardiovascularhigh-intensity interval exercisewalking function

Identifiers

PMID42205471
PMCPMC13208456

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.