ArticleJournal of education and health promotion2026
Diagnostic and prognostic role of platelet indices in pre-eclampsia: Insights from a hospital-based study in Eastern part of India.
Article in Journal of education and health promotion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPreeclampsia remains a major cause of maternal morbidity and mortality, characterized by hypertension and signs of organ dysfunction, including thrombocytopenia. Platelet indices such as mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), and platelet-large cell ratio (P-LCR) are emerging as potential biomarkers for preeclampsia severity and progression. To assess the association between platelet indices and preeclampsia among pregnant women attending antenatal care at a private healthcare facility in Bhubaneswar, Odisha. MATERIALS AND
methodsA hospital-based prospective case-control study was conducted, including pregnant women diagnosed with preeclampsia (both mild and severe) and normotensive controls. Platelet indices were measured at the time of delivery and compared across groups. Statistical analysis included ANOVA and
resultsA significant decrease in platelet count was observed in pre-eclamptic women compared to normotensive controls (mean platelet count: 2.38 ± 0.44 × 10
conclusionPlatelet indices, particularly PDW, MPV, and PCT, are significantly associated with preeclampsia and its severity. Incorporating these markers into routine antenatal screening could aid in early risk stratification. However, further multicenter studies and longitudinal follow-ups are recommended to establish standardized diagnostic cut-offs.
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