ArticleJournal of education and health promotion2026
Comparing ondansetron versus phenylephrine in reduce the incidence of hypotension after spinal anesthesia in cesarean section.
Article in Journal of education and health promotion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSpinal anesthesia is the method of choice for cesarean section (CS). This method poses risks such as maternal hypotension. Measures such as prescribing appropriate preventative medications can be an important strategy in the prevention and treatment of hypotension in mothers. MATERIALS AND
methodsThis quasi-experimental study was conducted at Arash Hospital, Tehran University of Medical Sciences, on 110 patients undergoing CS under spinal anesthesia. Then, patients who met the necessary conditions were randomly divided into one of two groups: ondansetron (
resultsThe mean age of all participants was 30.08 years, with a standard deviation of 5.90 years. Nausea occurred in 21 of the 110 participants (19.09%) during the surgical procedure. It was more common in the phenylephrine group, affecting 14 patients (25.45%), compared to only 7 patients (12.73%) in the ondansetron group (
conclusionThe findings revealed that while both agents were effective in managing maternal hemodynamics during surgery, ondansetron was associated with a significantly lower need for repeat antiemetic administration and reduced nausea and vomiting without increasing the risk of hypotension or bradycardia. Therefore, this finding may be useful for clinical practice and further studies.
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