Evidence map›Paper›PMID 42205284›Full record

ArticleRSC advances2026

Chalcone-sulfonate ester derivatives as dual urease and α-amylase inhibitors: synthesis, biological evaluation and integrated computational studies.

Zobia Noreen, Amina Sadiq, Nafeesa Naeem, Usama Raza, Ishtiaq Ahmed, Samar Y Al Nami, Aisha Hossan, Magdi E A Zaki, Ehsan Ullah Mughal

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Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zobia NoreenDepartment of Chemistry, Govt. College Women University Sialkot 51300 Pakistan amina.sadiq@gcwus.edu.pk.
Amina SadiqDepartment of Chemistry, Govt. College Women University Sialkot 51300 Pakistan amina.sadiq@gcwus.edu.pk.
Nafeesa NaeemDepartment of Chemistry, University of Gujrat Gujrat 50700 Pakistan ehsan.ullah@uog.edu.pk.ORCID https://orcid.org/0000-0002-6647-9697
Usama RazaDepartment of Pharmacognosy, Dow College of Pharmacy, Dow University of Health Sciences Karachi 74200 Pakistan.
Ishtiaq AhmedDepartment of Chemical Engineering and Biotechnology, University of Cambridge Cambridge UK.
Samar Y Al NamiDepartment of Chemistry, Faculty of Science, King Khalid University Abha Saudi Arabia.
Aisha HossanDepartment of Chemistry, Faculty of Science, King Khalid University Abha Saudi Arabia.
Magdi E A ZakiChemistry Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU) Riyadh Saudi Arabia.
Ehsan Ullah MughalDepartment of Chemistry, University of Gujrat Gujrat 50700 Pakistan ehsan.ullah@uog.edu.pk.ORCID https://orcid.org/0000-0001-9463-9398

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of chalcone-sulfonate ester derivatives (1-7) were synthesized and evaluated for their potential inhibitory activity against urease and α-amylase enzymes. The chemical structures of the synthesized compounds were confirmed using appropriate spectroscopic techniques (IR, NMR and mass spectrometry). The biological potential of these derivatives was assessed through

Identifiers

PMID42205284
PMCPMC13202438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.