Evidence map›Paper›PMID 42205252›Full record

ArticleSleep medicine: X2026

The Sentinel Sleep Theory: Unweaving the biological function of REM sleep.

Raffael Brito Spinassi

Abstract read
In one paragraph

Article in Sleep medicine: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Raffael Brito SpinassiAtibaia, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biological function of Rapid Eye Movement (REM) sleep remains one of neuroscience's great mysteries. In this theoretical research paper, I present the evolutionary theory that explains why REM sleep exists. I demonstrate that REM sleep functions to heighten brain alertness to significantly mitigate the high vulnerability inherent in non‑REM sleep-especially in deep sleep. Every organism with a nervous system must undergo non-REM sleep, a necessity that accompanies a negative and potentially lethal consequence: a higher risk of dying. Because non‑REM sleep substantially reduces alertness and increases the death risk, REM sleep evolved as an adaptive countermeasure, making it a

Identifiers

PMID42205252
PMCPMC13208913

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.