Evidence map›Paper›PMID 42205134›Full record

ArticleActa Cardiologica Sinica2026

Recurrence of Atrial Fibrillation After Repeat Catheter Ablation: A Systematic Review and Meta-Analysis.

Natee Deepan, Parinda Ansusinha, Adivitch Sripusanapan, Narathorn Kulthamrongsri, Thanaboon Yinadsawaphan, Pattara Rattanawong

Abstract read
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Article in Acta Cardiologica Sinica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Natee DeepanFaculty of Medicine, Chulalongkorn University.
Parinda AnsusinhaFaculty of Medicine, Srinakharinwirot University, Bangkok, Thailand.
Adivitch SripusanapanDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ.
Narathorn KulthamrongsriDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ.
Thanaboon YinadsawaphanDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ.
Pattara RattanawongDepartment of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Catheter ablation is a key treatment for atrial fibrillation (AF); however, recurrence often requires repeat procedures. This meta-analysis evaluates the efficacy of repeat ablation for recurrent atrial arrhythmia, focusing on ablation technique, anatomical targets, and pulmonary vein (PV) reconnection. Methods: A systematic literature search of MEDLINE, Scopus, and Cochrane Central Register of Controlled Trials was conducted on studies assessing repeat and initial ablation outcomes until February 2025. Data on atrial arrhythmia recurrence, ablation technique, targets, and PV reconnection were extracted. A random-effects model meta-analysis was used to estimate the pooled recurrence rate after repeat ablation. Results: Fifty-three studies (8,117 patients) were included. The recurrence rate after repeat ablation was 30% (95% confidence interval [CI]: 27%-34%), with PV reconnection observed in 90% of cases following the initial ablation. The lowest recurrence rate was observed with cryoballoon ablation (CBA) followed by radiofrequency ablation (RFA) at 23% (95% CI: 15%-33%, I Conclusions: Repeat ablation for AF was associated with the risk of recurrence, mainly due to PV reconnection. Strategies involving CBA followed by RFA and PVI-based approaches showed favorable outcomes, while lower reconnection rates in left-sided PVs, especially the LIPV, highlighting the need for optimized techniques.

Indexed as

Arrhythmia recurrenceAtrial fibrillationCardiac ablationCatheter ablationRepeat procedure

Identifiers

PMID42205134
PMCPMC13202364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.