Evidence map›Paper›PMID 42204941›Full record

ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Severe Toxicosis Secondary to Accidental Oclacitinib Ingestion in Three Cats.

Jessica Kielb Basile, Sara C Lister

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Severe Toxicosis Secondary to Accidental Oclacitinib Ingestion in Three Cats.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jessica Kielb BasileBluePearl Veterinary Partners, Levittown, Pennsylvania, USA.
Sara C ListerASPCA Poison Control, Champaign, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the clinical course, outcome, necropsy findings, possible mechanisms of toxicosis, and treatment implications for three cats with acute kidney injury and associated systemic signs secondary to accidental oclacitinib ingestion. SERIES SUMMARY: Three cats ingested large (>100 mg/kg) overdoses of oclacitinib, leading to severe acute kidney injury and associated systemic illness. Two of the three cats subsequently died or were euthanized, while the third cat made a full recovery after receiving intensive supportive care. Necropsies were performed on the two deceased cats, with no definitive mechanism for toxicosis identified. NEW OR UNIQUE INFORMATION PROVIDED: This is the first case series of accidental oclacitinib toxicosis in cats. Recognition of this emerging concern can aid clinicians in minimizing exposure risks where possible, as well as providing prompt treatment in overdose situations.

Indexed as

Acute Kidney InjuryCat DiseasesPyrimidinesSulfonamidesAnimalsCatsDrug OverdoseFatal OutcomeFemaleMaleoclacitinibPyrimidinesSulfonamidesAKIfelineJAK inhibitornephrotoxin

Identifiers

PMID42204941
PMCPMC13350347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.