Evidence map›Paper›PMID 42204536›Full record

ArticleBMC palliative care2026

ICD-10-based screening increased detection of hospitalisations potentially eligible for paediatric palliative care consultation in the emergency department: a validation study.

Vinícius de Mello, Marília Silveira de Almeida Campos, Natália de Araújo Neves, Thalita Zago Oliveira, João Paulo Vilela Rodrigues, Leila Costa Volpon, Marília Amaral Costa Frangiotti, Maria Olívia Barboza Zanetti, Leonardo Regis Leira Pereira, Fabiana Rossi Varallo

Abstract readValidation Study
In one paragraph

Article in BMC palliative care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Vinícius de MelloSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Marília Silveira de Almeida CamposSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Natália de Araújo NevesSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Thalita Zago OliveiraDepartment of Pharmacy, State University of Maringá, Maringá, Brazil.
João Paulo Vilela RodriguesSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Leila Costa VolponRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Marília Amaral Costa FrangiottiAmérico Brasiliense State Hospital, Américo Brasiliense, SP, Brazil.
Maria Olívia Barboza ZanettiSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Leonardo Regis Leira PereiraSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil.
Fabiana Rossi VaralloSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, 14040-900, Brazil. frvarallo@fcfrp.usp.br.

Funding

São Paulo Research Foundation (FAPESP) nº 23/04640-6 and nº 22/10857-5
6 · The paper itself

Abstract

backgroundDespite emergency departments (ED) having traditionally focused on disease reversal and survival goals, care in these settings also involves paediatric patients with life-limiting or life-threatening conditions (LLC/LTC) who experience acute exacerbations of their illnesses. Early identification of these patients may help address unmet needs and enhance care provision. We aimed to assess the performance of the International Classification of Diseases, 10th Revision (ICD-10)-based screening strategy to detect paediatric patients potentially eligible for paediatric palliative care (PPC) team consultation in a Brazilian ED.

methodsWe conducted a cross-sectional study of 1,000 paediatric hospitalisations in the ED of a tertiary teaching hospital in Brazil (March 2020-March 2021). Potentially eligible hospitalisations were screened using Himelstein's criteria, informed by ICD-10-based classifications of LLC/LTC, paediatric complex chronic conditions, and multidisciplinary PPC team input. Eligibility was confirmed through chart review and multidisciplinary discussion. Screening performance was evaluated using standard diagnostic accuracy measures.

resultsEighty-three hospitalisations were confirmed as potentially eligible for PPC consultation. The ICD-10-based strategy showed high sensitivity (0.99) and negative predictive value (1.00), with moderate specificity (0.73) and low positive predictive value (0.25). It increased case detection by 1.5-fold. Eligible hospitalisations were associated with younger age, higher mortality, and longer length of stay.

conclusionsICD-10-based screening was a high-sensitivity strategy for identifying paediatric hospitalisations potentially eligible for PPC consultation. Although not sufficient as a stand-alone diagnostic approach, it may support systematic case-finding and earlier identification of unmet PPC needs, particularly in settings with limited-service integration.

Indexed as

HospitalizationInternational Classification of DiseasesMass ScreeningPalliative CarePediatricsReferral and ConsultationAdolescentBrazilChildChild, PreschoolCross-Sectional StudiesEmergency Service, HospitalFemaleHumansInfantMaleEmergency Service, HospitalHealth Services Needs and DemandInternational Classification of DiseasesNeeds AssessmentPaediatricsPalliative Care

Identifiers

PMID42204536
PMCPMC13393898

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.