Evidence map›Paper›PMID 42204509›Full record

ArticleBMC neurology2026

Comparative anatomical and clinical evaluation of three surgical spaces for contralateral internal carotid artery C7-segment aneurysm clipping: the role of the subchiasmatic-preinfundibular space.

Xiaoliang Wang, Shiliang Wang, Shang Gao, Xuebin Wang, Yang Wu, Hailong Du, Chao Zhang, Lei Zhao, Xiaosong Liu, Xiaomeng Liu and 2 more

Abstract readComparative Study
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Xiaoliang Wang *Department of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Shiliang Wang *Department of Neurosurgery, Shijiazhuang People's Hospital, Shijiazhuang, 050031, China.
Shang GaoHebei Medical University, Shijiazhuang, 050017, China.
Xuebin WangHebei Medical University, Shijiazhuang, 050017, China.
Yang WuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Hailong DuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Chao ZhangDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Lei ZhaoDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Xiaosong LiuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Xiaomeng LiuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Gengshen ZhangDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China.
Jianliang WuDepartment of Neurosurgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang City, Hebei Province, 050000, China. wujianliang2000@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to anatomically define and clinically evaluate the subchiasmatic-preinfundibular space (SCPIS) as an alternative surgical space for clipping contralateral ICA C7-segment aneurysms, by comparing its outcomes with those of the standard prechiasmatic space (PCS) and contralateral opticocarotid space (OCS).

methodsBasic Research: Five cadaveric heads were dissected via the pterional approach. Contralateral ICA exposure was measured through three spaces- PCS, contralateral OCS), and SCPIS-before and after anterior clinoid process (ACP) drilling. Clinical Research: A retrospective analysis of 53 patients with multiple intracranial aneurysms (MIAs) treated via unilateral craniotomy compared outcomes across three groups: SCPIS (Group 1), PCS (Group 2), and contralateral OCS (Group 3). Postoperative aneurysm occlusion rates, complications, discharge mRS scores, and 6-month neurological deficits were assessed.

resultsThe lengths of the contralateral ICA exposure increased significantly post-ACP drilling: PCS (5.62 ± 0.91 mm vs. 7.11 ± 0.84 mm, p < 0.001), contralateral OCS (4.44 ± 2.33 mm vs. 6.03 ± 2.30 mm, p = 0.001), and SCPIS (4.98 ± 1.91 mm vs. 6.67 ± 2.01 mm, p < 0.001). Significant increases were also observed in the lengths of the inferior border of the optic chiasm and/or optic nerves, the deep superior border of the diaphragma sellae, and the area of this space after ACP drilling (p < 0.05). SCPIS clipping showed no significant differences in hospitalization duration, complications (pneumonia, electrolyte disturbances, optic nerve injury, cerebral infarction), or discharge mRS scores (p > 0.05) compared to other approaches. The rate of complete angiographic occlusion of the contralateral aneurysms was comparable among the three groups (PCS: 88.6%, OCS: 90.9%, SCPIS: 85.7%; p = 0.92). Six-month neurological outcomes were satisfactory.

conclusionSCPIS is a viable alternative for contralateral ICA C7-segment aneurysm clipping. ACP drilling improves surgical access, and the approach is safe and effective.

Indexed as

Carotid Artery, InternalCraniotomyIntracranial AneurysmNeurosurgical ProceduresAdultAgedCadaverFemaleHumansMaleMiddle AgedRetrospective StudiesSurgical InstrumentsTreatment OutcomeContralateral internal carotid arteryIntracranial multiple aneurysmsMicrosurgical anatomySubchiasmatic-preinfundibular spaceUnilateral craniotomy clipping

Identifiers

PMID42204509
PMCPMC13393927

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.