Observational studyBMC pulmonary medicine2026
A prospective observational pilot study assessing childhood asthma control in areas with increased urban environmental greenery.
Observational study in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
Funding
Abstract
objectiveThe purpose of this study is to assess the feasibility of measuring differences in asthma symptoms, lung function, asthma biomarkers, and allergic sensitization in children with asthma living in areas undergoing environmental greening compared to control areas.
methodsThis was a single-site prospective observational pilot study enrolling children living in either areas undergoing systematic environmental greening or in a designated control area. Eligible children were ages 6-18 with an asthma diagnosis. Children were followed for one year. The pre-specified primary endpoint was the change in Standardized Pediatric Asthma Quality of Life Questionnaire (PAQLQ(S)) scores between the initial and final visit. Secondary outcomes included changes in spirometry values, impulse oscillometry results, and asthma biomarkers (exhaled nitric oxide, IgE, blood eosinophils). Observational endpoints included healthcare utilization and self-reported rescue inhaler use. Urine samples were collected to measure plant metabolites. The trial was designed to provide key data to inform future larger studies in this domain.
resultsTen children in the control area (mean age 12.1 years) and nine children in the intervention area (mean age 11.9 years) with similar baseline PAQLQ(S) scores and lung function were enrolled. From initial to final measurement, mean PAQLQ(S) asthma symptom domain scores improved in children living in the intervention areas (baseline 5.4, final 6.1, p = 0.048) while scores in the control areas showed no change (baseline 5.6, final 5.2, p = 0.66). There were statistically significant declines in FEV
conclusionIn this small pilot study, children with asthma living in areas undergoing systematic environmental greening had improvements in asthma quality of life scores. Study interventions were feasible for subjects to complete. Larger studies with appropriate power are needed to study the direct impact of greening interventions on pediatric asthma.
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