Evidence map›Paper›PMID 42204371›Full record

ArticleCell death and differentiation2026

Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release.

Gaia Gherardi, Francesca Spinelli, Miriana Sbrissa, Martina Quagliata, Roberto Luisetto, Anna Scanu, Elena Vezzoli, Michela Carraro, Alva M Casey, Tiago F Branco and 9 more

Abstract read
PubMed Publisher
In one paragraph

Article in Cell death and differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Gaia Gherardi *Department of Biomedical Sciences, University of Padua, Padua, Italy.
Francesca Spinelli *Department of Biomedical Sciences, University of Padua, Padua, Italy.
Miriana SbrissaDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Martina QuagliataDepartment of Biomedical Sciences, University of Padua, Padua, Italy.
Roberto LuisettoDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Anna ScanuRehabilitation Unit, Department of Neuroscience, University of Padua, Padua, Italy.
Elena VezzoliALEMBIC Advanced Light and Electron Microscopy Experimental Imaging Center, IRCCS San Raffaele Scientific Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-3342-3451
Michela CarraroDepartment of Biomedical Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0002-4573-9306
Alva M CaseyMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-7242-3251
Tiago F BrancoDepartment of Biology, University of Padua, Padua, Italy.
Naotada IshiharaDepartment of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan.ORCID http://orcid.org/0000-0002-6305-7149
Andrea MattareiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0002-2023-0749
Stefano MasieroRehabilitation Unit, Department of Neuroscience, University of Padua, Padua, Italy.
Michael P MurphyMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
Paolo BernardiDepartment of Biomedical Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0001-9187-3736
Carlo TacchettiExperimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.
Luca ScorranoDepartment of Biology, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0002-8515-8928
Anna RaffaelloDepartment of Biomedical Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0002-8344-6459
Rosario RizzutoDepartment of Biomedical Sciences, University of Padua, Padua, Italy. rosario.rizzuto@unipd.it.ORCID http://orcid.org/0000-0001-7044-5097

Funding

Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) naFondazione Telethon (Telethon Foundation) GGP16029Ministero della Salute (Ministry of Health, Italy) RF-2016-02363566Ministero dell'Istruzione, dell'Università e della Ricerca (Ministry of Education, University and Research) PRIN 2020R28P2ERCUK | Medical Research Council (MRC) MC_UU_00028/4Università degli Studi di Padova (University of Padova) Stars 2017Wellcome Trust (Wellcome) 220257/Z/20/Z
6 · The paper itself

Abstract

Mitochondrial Ca

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.