Evidence map›Paper›PMID 42204356›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Delivery room resuscitation of conjoined twins.

K Taylor Wild, Natalie E Rintoul, Anne M Ades, Nahla Khalek, Juliana S Gebb, Edward R Oliver, Tom Reynolds, Leny Mathew, Heidi M Herrick, Kelle Matthews and 7 more

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

K Taylor WildDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA. wildk@chop.edu.ORCID http://orcid.org/0000-0002-0016-078X
Natalie E RintoulDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.
Anne M AdesDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-6299-5985
Nahla KhalekRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Juliana S GebbRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Edward R OliverRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Tom ReynoldsRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-5613-8696
Leny MathewRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Heidi M HerrickDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-0723-6898
Kelle MatthewsDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.
Lauren HeimallDivision of Neonatology, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.
Olivia NelsonRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-2930-138X
Benjamin B BruinsDepartment of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA, USA.
Jack RychikRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Emily A PartridgeRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Alan W FlakeRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-4913-7588
Holly L HedrickRichard D. Wood Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Funding

AHRQ HHS K08 HS029029U.S. Department of Health & Human Services | Agency for Healthcare Research and Quality (AHRQ) K08HS029029
6 · The paper itself

Abstract

objectiveDescribe the golden hour and hospital outcomes of conjoined twins

methodsRetrospective single center study of conjoined twins. Main outcome measures included delivery room characteristics. Secondary outcomes included survival and length of stay.

resultsFrom 2013-2025, there were 19 sets of conjoined twins (active resuscitation in 13; palliative in 6). Respiratory interventions in the delivery room were frequently needed including continuous positive airway pressure (75%), positive pressure ventilation (67%), and endotracheal intubation (25%). There were two sets with emergency separation, each with one surviving twin. For the 10 sets who underwent separation, survival at NICU discharge was 80% (twin A) and 100% (twin B).

conclusionThe delivery room resuscitation of conjoined twins is complex with high rates of advanced respiratory intervention. These deliveries necessitate an experienced multidisciplinary team and an individualized delivery plan based on specific anatomy and reinforced with simulation. Survival is high among twins who undergo separation.

Indexed as

Delivery RoomsResuscitationTwins, ConjoinedContinuous Positive Airway PressureDelivery, ObstetricFemaleHumansInfant, NewbornIntubation, IntratrachealLength of StayMalePositive-Pressure RespirationPregnancyRetrospective Studies

Identifiers

PMID42204356
PMCPMC13423802

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.