Evidence map›Paper›PMID 42204353›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Cannabis use, preterm birth, and small for gestational age: findings from the national birth defects prevention study.

Michelle R Klawans, Renata H Benjamin, Vahed Maroufy, Courtney E Byrd-Williams, Mark A Canfield, Zeyu Miao, Dorothy K Waller, National Birth Defects Prevention Study

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michelle R KlawansDepartment of Epidemiology, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA. michelle.klawans@gmail.com.ORCID http://orcid.org/0000-0002-0059-2400
Renata H BenjaminDepartment of Epidemiology, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA.
Vahed MaroufyDepartment of Biostatistics, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA.
Courtney E Byrd-WilliamsDepartment of Health Promotion and Behavioral Sciences, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin, TX, USA.
Mark A CanfieldDepartment of Epidemiology, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA.
Zeyu MiaoDepartment of Biostatistics, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA.
Dorothy K WallerDepartment of Epidemiology, The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX, USA.
National Birth Defects Prevention Study

Funding

U.S. Department of Health & Human Services | Centers for Disease Control and Prevention (CDC) U01DD000494
6 · The paper itself

Abstract

objectiveAs the prevalence of cannabis use continues to increase among women of reproductive age, studies exploring the impact of in utero cannabis exposure on birth outcomes are warranted. STUDY

designUsing data from the National Birth Defects Prevention Study, logistic regression was used to assess the relationship between maternal self-report of cannabis use during early pregnancy and 1) preterm birth, and 2) being born SGA. Patterns of cannabis use during the first six months of pregnancy were also assessed.

resultsThree percent of the sample (n = 324) reported cannabis use in early pregnancy. A slight majority (56%) of users ceased the use of cannabis after the second month of pregnancy. No significant association was observed between cannabis use and preterm birth (aOR = 1.27, 95% CI: 0.88-1.83) or SGA (aOR = 1.00, 95% CI: 0.68-1.47).

conclusionCannabis use in early pregnancy was not significantly associated with preterm birth or SGA in this sample.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.