Evidence map›Paper›PMID 42204037›Full record

ArticleInternational journal of clinical oncology2026

Outcomes of transmediastinal esophagectomy for patients with esophagogastric junction cancers.

Kotaro Sugawara, Koichi Yagi, Shoh Yajima, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Haruki Kojima, Raito Asaoka, Yoshifumi Baba

Abstract read
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In one paragraph

Article in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kotaro SugawaraDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. mayotic@hotmail.com.ORCID http://orcid.org/0000-0002-3272-1748
Koichi YagiDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Shoh YajimaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yoshiyuki MiwaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Shuichiro OyaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Asami OkamotoDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Haruki KojimaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Raito AsaokaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yoshifumi BabaDepartment of Gastrointestinal Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the outcomes of transmediastinal esophagectomy (TME) for esophagogastric junction cancer (EGJC) patients.

methodsWe retrospectively reviewed patients who underwent TME for EGJC (Siewert Type II) between 2018 and 2023. Robot-assisted TME was performed using a robotic surgical system (DaVinci). Postoperative complications, overall survival (OS) and disease-free survival (DFS) were investigated.

resultsThe median length of esophageal invasion was 3 cm. Adenocarcinoma was the most common tumor in our series (71.1%). A robotic approach was used for 25 (65.8%) patients. The most frequent major complication was pneumonia (≥ Grade I, n = 12, 31.6%), followed by recurrent laryngeal nerve palsy (≥ Grade I, n = 6, 15.8%). The incidence of anastomotic leakage (≥ Grade II) was 5.3% (n = 2). The 30-day mortality rate was 0%. The 3-year OS and DFS rates were 67.5 and 51.8%, respectively. The distribution of pathological LN metastases did not significantly demarcate OS curves (P = 0.43), while significantly stratifying DFS curves (P < 0.001). Patients with both mediastinal and abdominal LN metastases had very poor DFS (2-year DFS; 0%).

conclusionsTME for EGJC can be performed safely without increasing complications such as severe anastomotic leakage and in-hospital death. The relatively high frequency of pneumonia should be considered.

Indexed as

AdenocarcinomaEsophageal NeoplasmsEsophagectomyEsophagogastric JunctionAdultAgedDisease-Free SurvivalFemaleHumansLymphatic MetastasisMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRobotic Surgical ProceduresTreatment OutcomeAnastomotic leakageEsophagogastric junction cancerTransmediastinal esophagectomy

Identifiers

PMID42204037
PMCPMC13401529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.