Evidence map›Paper›PMID 42204029›Full record

ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2026

Indications, contraindications, and step-by-step methodology for performing carotid sinus massage in patients presenting with syncope : A scientific statement of an Ad Hoc Syncope Consortium endorsed by: the European Autonomic Society (EFAS), Gruppo Italiano Multidisciplinare Syncope (GIMSI) and European Geriatric Medicine Society (EuGMS).

Frederik J de Lange, Michele Brignole, David G Benditt, Melani Dani, Jean Claude Deharo, Alessandra Fanciulli, Artur Fedorowski, Antonella Groppelli, Mohamed H Hamdan, Viktor Hamrefors and 20 more

Abstract readConsensus StatementReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Frederik J de LangeDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Heart Centre, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands. f.j.delange@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-7590-9230
Michele BrignoleDepartment of Cardiology Milan, IRCCS Istituto Auxologico Italiano, Milan, Italy.
David G BendittCardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Melani DaniDepartment of Bioengineering Cutrale Perioperative and Ageing Group, Imperial College London, London, W12 0BZ, UK.
Jean Claude DeharoAssistance Publique, Hôpitaux de Marseille, Service de Cardiologie, Centre Hospitalier Universitaire La Timone, Marseille, France.
Alessandra FanciulliDepartment of Neurology, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Artur FedorowskiDepartment of Cardiology, Karolinska University Hospital, Department of Medicine, Karolinska Institute, Stockholm, Sweden.
Antonella GroppelliDepartment of Cardiology Milan, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Mohamed H HamdanDivision of Cardiovascular Medicine, Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Viktor HamreforsDepartment of Clinical Sciences, Lund University, Malmö, Sweden.
Jelle S Y de JongDepartment of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, Heart Centre, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.
Rose Anne KennyTrinity College and St James Hospital, Dublin, Ireland.
Piotr KulakowskiDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, 04-073, Warsaw, Poland.
Angel MoyaDepartment of Cardiology, Hospital Universitari Dexeus, 08028, Barcelona, Spain.
Roberto MaggiDepartment of Cardiology, Ospedali del Tigullio, Lavagna, Italy.
Carlos A MorilloLibin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Brian OlshanskyDivision of Cardiology, Department of Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Satish R RajLibin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Ciara RiceTrinity College and St James Hospital, Dublin, Ireland.
Giulia RivasiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Ineke van RossumDepartment of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.
Vincenzo RussoDepartment of Translational Medical Sciences, Cardiology and Syncope Unit, University of Campania 'Luigi Vanvitelli', Monaldi Hospital, Piazzale E. Ruggeri, 80126, Naples, Italy.
Robert SheldonLibin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Win-Kuan ShenDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, USA.
Richard SuttonDepartment of Cardiology, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.
Roland ThijsDepartment of Neurology, Leiden University Medical Centre, Leiden, the Netherlands.
Patricia TaraborrelliImperial Syncope Unit, Imperial College Healthcare NHS Trust, London, W12 0HS, UK.
Marco TomainoDivision of Cardiology, Ospedale Generale Regionale, Bolzano, Italy.
Andrea UngarDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Steven van ZantenDepartment of Cardiology, Reinier de Graaf Gasthuis, Delft, The Netherlands.ORCID http://orcid.org/0009-0005-1784-9558

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotid sinus massage (CSM) is essential in evaluating recurrent unexplained reflex syncope, as it uniquely identifies cardioinhibitory forms that other tests may miss. CSM is largely underused in clinical practice outside dedicated syncope facilities and, when performed, its execution varies, as does the interpretation of results. Underuse affects the diagnostic yield of CSM in the syncope evaluation, thereby denying patients mechanism-based personalized treatment. There are several barriers to the proper use of CSM in the work-up of patients with unexplained syncope.To address these important limitations, an international panel of experts in the field of syncope provide herein a consensus document with the aim of offering practical guidance for the indications, contraindications, and methodology for performing carotid sinus massage in general and dedicated syncope facilities and in the emergency department.

Indexed as

Carotid SinusMassageSocieties, MedicalSyncopeEuropeHumansCarotid sinus massageClinical practiceDiagnosticSyncope

Identifiers

PMID42204029
PMCPMC13461681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.