Evidence map›Paper›PMID 42204012›Full record

ArticleJournal of materials science. Materials in medicine2026

Hemocompatibility and cytotoxicity evaluation of additively manufactured and surface-treated 316 L stainless steel aortic stents using laser powder bed fusion (L-PBF).

Philipp Lulla, Lukas Esper, Ulf Noster, Thomas Schratzenstaller, Christof Schmid, Karla Lehle

Abstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Philipp LullaLaboratory for Medical Devices, Faculty of Mechanical Engineering, Technical University of Applied Sciences (OTH) Regensburg, Regensburg, Germany. philipp.lulla@oth-regensburg.de.ORCID http://orcid.org/0009-0007-6896-9845
Lukas EsperMaterial Science and Surface Analytic Lab, OTH Regensburg, Regensburg, Germany.ORCID http://orcid.org/0000-0002-6205-0463
Ulf NosterMaterial Science and Surface Analytic Lab, OTH Regensburg, Regensburg, Germany.ORCID http://orcid.org/0009-0009-7088-1767
Thomas SchratzenstallerLaboratory for Medical Devices, Faculty of Mechanical Engineering, Technical University of Applied Sciences (OTH) Regensburg, Regensburg, Germany.
Christof SchmidDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.
Karla LehleDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.

Funding

Bundesministerium für Bildung und Forschung 13GW0391B
6 · The paper itself

Abstract

New developments are needed in aortic replacement, with current hybrid solutions suffering from insufficient and rigid stent diameters, thus hindering minimization of false lumen in aortic dissection. Laser powder bed fusion (L-PBF) is an attractive method to generate a new-generation aortic stent. This study investigates the effects of 316 L stainless steel samples manufactured using the L-PBF process on the activity of fibroblasts, red blood cells, leukocytes and platelets on the modified surfaces. Cytotoxicity and hemocompatibility were analyzed under static culture conditions using immunofluorescence as well as scanning electron microscopic (SEM) techniques. Surfaces of additively manufactured samples were etched, electropolished, heat‑treated, and mechanically expanded to optimize the material's mechanical performance. Alone heat treatment increased the ultimate tensile strength from 585 ± 5 MPa to 695 ± 6 MPa. The additive manufactured and post-processed stents were non-cytotoxic (viability, > 70%, independent of the manufacturing status), non-hemolytic (hemolysis rate, < 1%), and were covered with only a few neutrophils (median (IQR), 25 (12-48) per mm

Indexed as

AortaBiocompatible MaterialsBlood Vessel ProsthesisLasersStainless SteelStentsAnimalsBlood PlateletsCell SurvivalFibroblastsHemolysisHumansLeukocytesMaterials TestingMicroscopy, Electron, ScanningPowdersBiocompatible MaterialsPowdersStainless Steel

Identifiers

PMID42204012
PMCPMC13216169

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.