SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
From evidence to action: Italian recommendations for the diagnosis and treatment of spatial neglect in stroke patients.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpatial neglect is a common and disabling cognitive consequence of stroke, associated with reduced functional independence, prolonged hospitalization, and increased healthcare and societal burden.
objectiveThe aim of this paper is to describe the development of a Clinical Practice Guideline (CPG) for the diagnosis and treatment of spatial neglect in stroke patients.
methodsThe guideline was developed by an interdisciplinary expert Panel following the GRADE approach, supported by systematic reviews of the literature. Four clinical questions addressed the effectiveness of prism adaptation therapy (PAT) and visuospatial training (VST), optimal timing of treatment initiation, and the accuracy of neglect-specific versus generic ADL assessment tools.
resultsEvidence from randomized controlled trials indicates that both PAT and VST yield small, short-term improvements in ADL performance and neglect severity; however, overall certainty of evidence remains very low due to methodological limitations. Based on this evidence, the Panel developed two conditional recommendations in favor of using PAT and VST for the rehabilitation of patients with peri-personal neglect. No studies examined optimal timing, leading the Panel to issue Good Practice Statements recommending initiation within 4-7 days post-stroke. Observational evidence supports the use of neglect-specific tools, particularly the Catherine Bergego Scale (KF-NAP version) and the semi-structured Zoccolotti scale, which outperform generic ADL measures.
conclusionsThis CPG represents the first coordinated national effort in Italy to standardize the diagnosis and rehabilitation of post-stroke spatial neglect within the National Health Service. The CPG provides two conditional recommendations for treatments along with practical indications to support implementation and future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.