Evidence map›Paper›PMID 42203882›Full record

ArticleNature2026

Human haematopoietic stem cells remember inflammatory stress.

Andy G X Zeng, Murtaza S Nagree, Niels Asger Jakobsen, Sayyam Shah, Angelica Varesi, Jasmine Ryu Won Kang, Alex Murison, Jin-Gyu Cheong, Sven Turkalj, Xuan Zhang and 27 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Neonatal critical illness is associated with pancytopenia development in childhood.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. AbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Andy G X Zeng *Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Murtaza S Nagree *Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-4877-6241
Niels Asger Jakobsen *MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-5776-5085
Sayyam ShahPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Angelica VaresiPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Jasmine Ryu Won KangPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Alex MurisonPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Jin-Gyu CheongDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Sven TurkaljMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Xuan ZhangDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-7966-8748
Felix A RadtkeMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-6491-2573
Tsega-Ab AberaDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Isabel N X LimPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Liqing JinPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Joana AraújoDepartment of Hematology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Alicia G Aguilar-NavarroPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Darrien ParrisPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7725-6213
Jessica McLeodPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Hyerin KimPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Ho Seok LeePrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0009-0009-5892-543X
Lin ZhangPeter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Mason BoulangerPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Elyssa BaderDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Elias GbehaOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Christopher N ParkhurstDivision of Pulmonary and Critical Care Medicine, Weill Cornell Graduate School, NewYork, NY, USA.
Elvin WagenblastPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-0709-2759
Eugenia Flores-FigueroaPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-7453-1125
Bo WangPeter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Gregory W SchwartzPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-4003-3045
Leonard D ShultzThe Jackson Laboratory, Bar Harbor, ME, USA.
Anna S NamDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
H Leighton GrimesDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-8162-6758
Steven Z JosefowiczDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-7453-779X
Philip AwadallaNuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.
Paresh VyasMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-3931-0914
John E DickPrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-9527-8317
Stephanie Z XiePrincess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. stephanie.xie@uhn.ca.ORCID http://orcid.org/0000-0002-0284-494X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation activates blood cells, contributing to ageing and malignancy

Indexed as

Hematopoietic Stem CellsInflammationStress, PhysiologicalAdultAgingAnemia, Sickle CellAnimalsCell DifferentiationChildClonal HematopoiesisCOVID-19FemaleHematopoiesisHeterograftsHumansMale

Identifiers

PMID42203882
PMCPMC13345971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.