Evidence map›Paper›PMID 42203279›Full record

ArticleBMJ open2026

Feasibility and acceptability of therapist-guided, asynchronous, internet-delivered trauma-focused CBT for adolescents with PTSD: a single-group feasibility trial in Sweden.

Erica Mattelin, Hanna Weyler, Rebecca Andersson, Josefine Paulsen, Sandra Tielman, Anna Vikgren, Kristina Bondjers, Eva Serlachius, David Mataix-Cols, Maria Bragesjö

Registry-linked trialAbstract readClinical Study
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06185244 (Efficacy and Cost Effectiveness of Internet-delivered Trauma-focused CBT for Young People With PTSD), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06185244 narecruitingnot on this map

Efficacy and Cost Effectiveness of Internet-delivered Trauma-focused CBT for Young People With PTSD

TypeinterventionalSponsorKarolinska InstitutetRan2024 to 2028Enrolled240ConditionsPosttraumatic Stress DisorderArmsTherapist-supported internet-delivered trauma-focused CBT, 12 weeks of therapist-supported internet-delivered psychoeducation and stress management/relaxation for both the youth and the care giver.
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erica MattelinCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Sweden erica.mattelin@ki.se.ORCID http://orcid.org/0000-0002-0796-3921
Hanna WeylerSave the Children, Stockholm, Stockholm County, Sweden.
Rebecca AnderssonCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0284-0893
Josefine PaulsenSave the Children, Stockholm, Stockholm County, Sweden.
Sandra TielmanSave the Children, Stockholm, Stockholm County, Sweden.
Anna VikgrenSave the Children, Stockholm, Stockholm County, Sweden.
Kristina BondjersNational Centre for Disaster Psychiatry, Uppsala University Department of Medical Sciences, Uppsala, Uppsala County, Sweden.ORCID http://orcid.org/0000-0001-7062-1011
Eva SerlachiusDepartment of Clinical Neuroscience, Karolinska Institute Centre for Psychiatry Research, Stockholm, Stockholm County, Sweden.
David Mataix-ColsCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Sweden.
Maria BragesjöCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, and Stockholm Health Care Services, Region Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTrauma-focused cognitive behavioural therapy (TF-CBT) is the established first-line treatment for paediatric post-traumatic stress disorder (PTSD), but access to evidence-based care remains limited. This study aimed to evaluate the feasibility and acceptability of a therapist-guided, 12 week, internet-delivered TF-CBT (iTF-CBT) programme for adolescents with PTSD and to explore preliminary changes in PTSD symptoms.

designSingle-group feasibility trial.

settingSave the Children, Sweden.

participantsTwenty-two adolescents (13-17 years, 82% female) with primary PTSD.

interventionsA 12 week, therapist-guided, asynchronous, internet-delivered TF-CBT comprising eight modules and parallel caregiver modules with joint adolescent-caregiver activities. OUTCOMES: Feasibility measures included recruitment pace, participant retention, treatment adherence (module completion) and therapist time. Acceptability was evaluated through satisfaction, credibility, negative effects and reported adverse events. Within-group changes in PTSD severity using independent evaluator-rated Clinician-Administered PTSD Scale (CAPS-CA-5) and the self-reported Child and Adolescent Trauma Screen 2 (CATS-2) were used as indicators of potential clinical change. Assessments occurred at baseline, during treatment, post-treatment and at 1 month follow-up (primary endpoint).

resultsRecruitment was completed after 7 months of active enrolment. Retention and adherence were high, satisfaction and credibility ratings were favourable, and no intervention-related serious adverse events occurred. Within-group improvements were observed at the primary endpoint, with large reductions on CAPS-CA-5 (Cohen's d=1.27) and CATS-2 (Cohen's d=1.51). At follow-up, 47.6% of participants no longer met criteria for PTSD.

conclusionsTherapist-guided iTF-CBT for adolescents with PTSD was safe, feasible, acceptable and associated with potentially meaningful symptom improvements. These findings support further evaluation in larger, controlled trials to determine efficacy, cost-effectiveness and long-term outcomes. TRIAL REGISTRATION NUMBER: NCT06185244.

Indexed as

Cognitive Behavioral TherapyInternetInternet-Based InterventionPatient Acceptance of Health CareStress Disorders, Post-TraumaticAdolescentFeasibility StudiesFemaleHumansMaleMental Health TeletherapySwedenTreatment OutcomeAdolescentsChild & adolescent psychiatryDigital TechnologyGender-Based ViolenceInternetStress Disorders, Traumatic, Acute

Identifiers

PMID42203279
PMCPMC13218193

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.