ArticleScience advances2026
Bioelectric calcium transport and activation in mammalian cells using field-focused DNA-carbon nanotube meshes.
Haodong Li, Yuyao Li, Jia Liao, Changming Bao, Xiaodi Cao, Xinping Gao, Wenjian Luo, Tao Ding, Weiming Lin, Xizhi Deng and 5 more
Abstract read
In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
15 authors.
Haodong LiThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.ORCID 0009-0006-5448-2465 Yuyao LiCollege of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
Jia LiaoDepartment of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.ORCID 0000-0001-7907-9994 Changming BaoThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.ORCID 0009-0008-2739-056X Xiaodi CaoZhangjiang Laboratory, Shanghai 201210, China.
Xinping GaoThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.
Wenjian LuoThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.
Tao DingThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.
Weiming LinThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.ORCID 0009-0002-9484-5057 Xizhi DengThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.
Mingxing XieDepartment of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.ORCID 0000-0003-4984-1567 Chunhai FanSchool of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0002-7171-7338 Le LiangThe Institute for Advanced Studies (IAS), State Key Laboratory of Metabolism and Regulation in Complex Organisms, Wuhan University, Wuhan 430072, China.ORCID 0000-0001-6682-959X Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Electrical signaling in biology is ionic. Safe modulation needs interfaces that couple electrons to ions at soft membranes without injury. We present DNA-FOCUS, a membrane-conformal, DNA-programmed carbon-nanotube biointerface that self-assembles on living cells, weaving DNA-wrapped SWCNTs into an ultraflexible mesh. A subvolt bias is condensed into nanometer hotspots at the membrane, lowering access resistance and engaging endogenous calcium-permeable ion channels. Subvolt stimulation drives sustained Ca
Indexed as
CalciumDNANanotubes, CarbonAnimalsElectroporationElectroporation TherapiesHumansPerforinCalciumDNANanotubes, CarbonPerforin
Identifiers
PMID42202034
PMCPMC13215216
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LicenceCC BY-NC
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