Evidence map›Paper›PMID 42201622›Full record

ArticleDiscover oncology2026

Investigation of the clinical value of artificial intelligence-derived prognostic signature in cervical cancer based on machine learning algorithms.

Chao Xu, Hang Li, Yuxuan Wu, Qiuming Yao, Yanbo Zhong

Abstract read
In one paragraph

Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chao Xu *Department of Obstetrics and Gynecology, Minhang Hospital, Fudan University, 170 Xinsong Road, Minhang District, Shanghai, 201199, China.
Hang Li *Department of Obstetrics and Gynecology, Minhang Hospital, Fudan University, 170 Xinsong Road, Minhang District, Shanghai, 201199, China.
Yuxuan WuDepartment of Obstetrics and Gynecology, Minhang Hospital, Fudan University, 170 Xinsong Road, Minhang District, Shanghai, 201199, China.
Qiuming YaoDepartment of General Practice, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Xuhui District, Shanghai, 200032, China. yaoqiuming@fudan.edu.cn.
Yanbo ZhongDepartment of Obstetrics and Gynecology, Minhang Hospital, Fudan University, 170 Xinsong Road, Minhang District, Shanghai, 201199, China. zhong_yanbo@fudan.edu.cn.

Funding

Shanghai Sailing Program 23YF1405300
6 · The paper itself

Abstract

Women around the world are troubled by life-threatening cervical cancer. It is urgent to identify a biomarker to improve the prognosis of cervical cancer patients. Based on gene expression profiles and single-cell sequencing data obtained from public databases, we performed dimensionality reduction and clustering analyses, Scissor analysis, WGCNA, and machine-learning modeling using 10 base algorithms and their 101 individual or combined strategies. We finally screened 24 consensus prognostic genes to develop a novel model artificial intelligence-derived prognostic signature (AIDPS), based on C-index which was detected in six validation datasets (TCGA_Test, TCGA_Entire, CGCI-HTMCP-CC, GSE39001, GSE44001, and GSE52903). AIDPS demonstrated modest but consistent prognostic performance across multiple independent cervical cancer cohorts, with an average C-index of 0.665.The accuracy of AIDPS in predicting CESC was significantly better than that of other clinical characteristics including age, pathological TNM stages, and grade. In conclusion, our study developed a consensus model AIDPS, an effective strategy to further guide the clinical management and individualized treatment of cervical cancer.

Indexed as

AIDPSCervical cancerClinical guidanceMachine learningPrognosis

Identifiers

PMID42201622
PMCPMC13396318

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.