Evidence map›Paper›PMID 42201382›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Influence of Antithrombotics on Severely Injured Patients Over 50 With Blunt Abdominal Trauma.

Nicolas Eibinger, Belinda Limberger, Nina Hörlesberger, Paul Puchwein, Rolf Lefering, Tobias Peter Bayer, Jonin Serafin Zumsteg, Hans-Christoph Pape, Kai Oliver Jensen

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nicolas EibingerDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, 8036, Austria. nicolas.eibinger@medunigraz.at.
Belinda LimbergerDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, 8036, Austria.
Nina HörlesbergerDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, 8036, Austria.
Paul PuchweinDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, 8036, Austria.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), University Witten/Herdecke, Cologne, Germany.
Tobias Peter BayerDepartment of Trauma, University Hospital Zurich, Zurich, Switzerland.
Jonin Serafin ZumstegDepartment of Trauma, University Hospital Zurich, Zurich, Switzerland.
Hans-Christoph PapeDepartment of Trauma, University Hospital Zurich, Zurich, Switzerland.
Kai Oliver JensenDepartment of Trauma, University Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSevere abdominal trauma represents a critical subset of injuries, particularly in the aging European population, where the prevalence of preexisting anticoagulant or antiplatelet therapy is increasing. While the impact of such medications on outcomes in traumatic brain injury is well studied, limited data exist regarding their influence in patients with abdominal trauma. MATERIALS AND

methodsThis retrospective cohort study used data from the TraumaRegister DGU

resultsOf 328,281 patients, 4,069 met inclusion criteria (2,831 NM; 1,238 ATM). Patients in the AM group were older (74.1 vs. 62.3 years) and had higher mortality (25.0% vs. 10.4%), particularly in the DOAC subgroup (30.3%). SMR analysis demonstrated increased mortality in the AM group compared to expected rates. In multivariate logistic regression, antithrombotic medication remained an independent predictor of mortality (OR 1.28, 95% CI 1.03-1.58; p = 0.025). Prehospital management differed significantly, with lower intubation and tranexamic acid use in the AM group. Surgical management was largely comparable.

conclusionAntithrombotic therapy is independently associated with increased mortality in patients aged ≥ 50 years with severe abdominal trauma. In addition to distinct treatment patterns and possible undertriage, these findings highlight the need for tailored trauma management strategies in this high-risk population.

Indexed as

Abdominal InjuriesFibrinolytic AgentsWounds, NonpenetratingAgedAged, 80 and overAustriaFemaleGermanyHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedRegistriesRetrospective StudiesSwitzerlandFibrinolytic AgentsAbdominal traumaAntithrombotic medicationBlunt traumaGeriatic traumaMortality risk

Identifiers

PMID42201382
PMCPMC13216133

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