Evidence map›Paper›PMID 42201234›Full record

SynthesisAdvances in respiratory medicine2026

Association Between Air Pollution and Childhood Asthma: A Systematic Review of Recent Evidence.

Maria Kyrmanidou, Ioannis Smaraidos, Asterios Kampouras

Abstract readSystematic Review
In one paragraph

Synthesis in Advances in respiratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria Kyrmanidou4th Pediatric Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ioannis SmaraidosDepartment of Economics, Directorate of Academics, Hellenic Military Academy of Combat Support Officers, 54636 Thessaloniki, Greece.
Asterios Kampouras4th Pediatric Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0001-7047-9449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAir pollution is a major environmental determinant of respiratory health and a significant contributor to the global burden of childhood asthma. Although several recent narrative and systematic reviews have examined environmental triggers of asthma, highlighting air pollution as a consistent risk factor across diverse populations and study designs, recent epidemiological evidence-including multicenter cohort studies and region-specific analyses from Europe and Greece-has not been systematically synthesized.

objectiveTo systematically review recent epidemiological evidence (2000-2025) on the association between ambient air pollution and childhood asthma incidence and exacerbations, with emphasis on European and Greek populations.

methodsFollowing PRISMA guidelines, we systematically reviewed observational studies published between 2000 and 2025 in PubMed, Scopus, Web of Science, BMC, and Google Scholar. Studies evaluating quantitative exposure to PM

resultsTwenty-four studies involving more than 3.5 million children were included. Consistent associations were observed across international and European cohorts between long-term exposure to PM

conclusionsThis review provides an updated synthesis of 21st-century evidence demonstrating that ambient air pollution is a major and modifiable determinant of childhood asthma. The consistency of findings across regions, combined with limited longitudinal evidence from Greece, highlight the importance of improved air-quality management and continued public-health efforts to reduce exposure and the need for enhanced epidemiological monitoring.

Indexed as

Air PollutionAsthmaEnvironmental ExposureAir PollutantsChildGreeceHumansIncidenceParticulate MatterRisk FactorsAir PollutantsParticulate Matterair pollutionchildhood asthmanitrogen dioxidepediatric respiratory healthPM10PM2.5

Identifiers

PMID42201234
PMCPMC13214496

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.