Evidence map›Paper›PMID 42201135›Full record

ArticleMuscles (Basel, Switzerland)2026

Open-Source Tools for Neuromuscular Electrical Stimulation in Mouse Models: A Methodological Validation Study.

Bana H Odeh, Amanda L Wellman, Michael Ameye, Zachary Atwood, Luke Gray, Aiswarya Saravanan, Havish Poluru, Morium Begam, Takako I Jones, Renuka Roche and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Muscles (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bana H OdehPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Amanda L WellmanPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.ORCID 0009-0006-1374-0755
Michael AmeyePhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Zachary AtwoodPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Luke GrayPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Aiswarya SaravananPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.ORCID 0009-0000-9619-4345
Havish PoluruPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Morium BegamPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Takako I JonesDepartment of Pharmacology, School of Medicine, University of Nevada, Reno, NV 89557, USA.ORCID 0000-0002-1578-4085
Renuka RocheOccupational Therapy Program, School of Health Sciences, Eastern Michigan University, Ypsilanti, MI 48197, USA.
Joseph A RochePhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-9497-6850

Funding

U.S. National Institutes of Health P2CHD086843U.S. National Institutes of Health R01AR079884U.S. National Institutes of Health R03HD091648
6 · The paper itself

Abstract

Neuromuscular electrical stimulation (NMES) is integral to studying muscle function in healthy and dystrophic mice. Certain commercial electrodes and laboratory stimulators used for NMES in mice are no longer in production. We developed and/or tested low-cost, open-source alternatives to discontinued commercial standards. We performed two studies-a comparison of electrodes and a comparison of stimulators. In the electrode study, in vivo NMES was applied to the left hindlimb ankle dorsiflexors in healthy C57BL/6J and dysferlin-null BLAJ mice using three electrode types: a previously available commercial electrode, a custom 3D-Printed electrode, and a custom Pen electrode assembled from off-the-shelf components. Twitch and tetanic torque were measured and compared using two-way repeated-measures ANOVA. Twitch torque differed by electrode type (

Indexed as

dysferlinopathyelectrodesmouse modelsneuromuscular electrical stimulationopen-sourcestimulators

Identifiers

PMID42201135
PMCPMC13214815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.