ArticleMedical sciences (Basel, Switzerland)2026
Loss of PTEN as an Independent Poor Prognosis Indicator in Lung Adenocarcinoma, but Not in Squamous Cell Carcinoma, Is Associated with an Immunosuppressive Tumor Microenvironment and Distinct Co-Mutational Profiles.
Maeva Houry, Shannon J Silva, Maider Artola, Carmen Behrens, Katerina Politi, Ignacio Wistuba, Luis Montuenga, Francisco Exposito, Alfonso Calvo
Abstract read
In one paragraphArticle in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Maeva HouryProgram in Solid Tumors, Center for Applied Medical Research (CIMA), Cancer Center Clinica Universidad de Navarra (CCUN), University of Navarra, Avenida de Pío XII, 55, 31008 Pamplona, Spain.
Shannon J SilvaDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-5562-1512 Maider ArtolaDepartment of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0009-0003-0991-700X Carmen BehrensDepartment of Translational Molecular Pathology, UTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Katerina PolitiDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.
Ignacio WistubaDepartment of Translational Molecular Pathology, UTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Luis MontuengaProgram in Solid Tumors, Center for Applied Medical Research (CIMA), Cancer Center Clinica Universidad de Navarra (CCUN), University of Navarra, Avenida de Pío XII, 55, 31008 Pamplona, Spain.ORCID 0000-0002-8739-1387 Francisco ExpositoDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.ORCID 0000-0002-5406-0768 Alfonso CalvoProgram in Solid Tumors, Center for Applied Medical Research (CIMA), Cancer Center Clinica Universidad de Navarra (CCUN), University of Navarra, Avenida de Pío XII, 55, 31008 Pamplona, Spain.ORCID 0000-0003-4074-4242 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
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Indexed as
Adenocarcinoma of LungCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellLung NeoplasmsPTEN PhosphohydrolaseTumor MicroenvironmentBiomarkers, TumorFemaleHumansMaleMutationPrognosisBiomarkers, TumorPTEN PhosphohydrolasePTEN protein, humanimmune populationslung adenocarcinomalung squamous carcinomamutation patternsprognosisPTEN
Identifiers
PMID42201046
PMCPMC13214857
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