ArticleMedical sciences (Basel, Switzerland)2026
Regulatory Variation at TERT and TERC Shows Limited Association with Early-Onset Alzheimer's Disease in Carriers of the Mexican Founder Mutation
Celeste Patricia Gazcón-Rivas, Iliannis Yisel Roa-Bruzón, Luis Félix Duany-Almira, Cesar Aly Valdéz-Gaxiola, Sofia Dumois-Petersen, Luis Eduardo Figuera-Villanueva, Antonio Quintero-Ramos, Carmen Magdalena Gurrola-Díaz, Daniel Ortuño-Sahagun, Yeminia Valle and 1 more
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In one paragraphArticle in Medical sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
11 authors.
Celeste Patricia Gazcón-RivasPrograma de Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Iliannis Yisel Roa-BruzónPrograma de Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-8713-3089 Luis Félix Duany-AlmiraPrograma de Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0001-9443-7905 Cesar Aly Valdéz-GaxiolaPrograma de Doctorado en Genética Humana, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Sofia Dumois-PetersenCentro Universitario de los Valles, Departamento de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 46708, Jalisco, Mexico.ORCID 0009-0003-5858-8978 Luis Eduardo Figuera-VillanuevaDivisión de Genética, Centro de Investigación Biomédica de Occidente (CIBO), Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Jalisco, Mexico.
Antonio Quintero-RamosInstituto de Investigación en Inmunología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0001-5963-9712 Carmen Magdalena Gurrola-DíazInstituto de Investigación en Enfermedades Crónico Degenerativas, Centro Universitario de Ciencias de la Salud (CUCS), Departamento de Biología Molecular y Genómica, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-9851-8961 Daniel Ortuño-SahagunInstituto de Neurociencias Traslacionales, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-7443-2514 Yeminia ValleInstituto de Neurociencias Traslacionales, Departamento de Neurociencias, Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-4940-022X Oscar Arias-CarriónDivisión de Neurociencias Clínica, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra, Mexico City 14389, Mexico.ORCID 0000-0002-9982-7571 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
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Indexed as
Alzheimer DiseasePresenilin-1RNATelomeraseAge of OnsetCase-Control StudiesCross-Sectional StudiesFemaleFounder EffectGene FrequencyGenetic Predisposition to DiseaseGenotypeHeterozygoteHumansMaleMexicoPresenilin-1PSEN1 protein, humanRNATelomerasetelomerase RNATERT protein, humanearly-onset Alzheimer’s diseasegenetic modifiersPSEN1telomere biologyTERCTERT
Identifiers
PMID42201020
PMCPMC13214640
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