Evidence map›Paper›PMID 42200603›Full record

ReviewBioanalysis

Recent developments in analytical techniques for monitoring anabolic-androgenic steroids in biological and environmental matrices: challenges and future opportunities.

Nouf M Alourfi

Abstract readReview
In one paragraph

Review in Bioanalysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nouf M AlourfiDepartment of Chemistry, Arts and Sciences College, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anabolic-androgenic steroids (AAS) are widely used in clinical practice but are also frequently misused, necessitating reliable analytical methods for their detection in biological and environmental matrices. This review summarizes recent developments in analytical techniques for AAS determination between 2011 and 2024, with emphasis on chromatographic and mass spectrometric approaches. Relevant literature was identified through searches of major scientific databases, including Scopus, Web of Science, and PubMed, using keywords related to anabolic-androgenic steroids and analytical detection methods; studies were selected based on relevance to methodological advances. Gas chromatography-mass spectrometry (GC-MS) remains a robust platform, with high-resolution GC-HRMS enhancing selectivity and retrospective analysis capabilities. Liquid chromatography-mass spectrometry (LC-MS/MS) provides high sensitivity and throughput for targeted quantification, while LC-HRMS enables broader screening through suspect and non-targeted approaches. Advances in sample preparation, including microextraction and automated workflows, have improved analytical efficiency and reduced matrix effects. Emerging platforms such as ion mobility spectrometry and ambient ionization methods offer rapid screening but remain complementary to established techniques. Overall, modern AAS analysis reflects a shift toward integrated analytical strategies combining targeted and high-resolution approaches to address increasing analytical complexity and evolving regulatory demands.

Indexed as

Anabolic AgentsAnabolic Androgenic SteroidsEnvironmental MonitoringAnimalsGas Chromatography-Mass SpectrometryHumansLiquid Chromatography-Mass SpectrometryTandem Mass SpectrometryAnabolic AgentsAnabolic Androgenic SteroidsAnabolic–androgenic steroidsanalytical chemistrybiological matriceschromatographic techniquesenvironmental analysishigh-resolution mass spectrometryLC–MS/MSmass spectrometrysample preparation

Identifiers

PMID42200603
PMCPMC13313190

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.