Evidence map›Paper›PMID 42200513›Full record

ArticleMicrobial genomics2026

Integrative and conjugative elements carrying high-level gentamicin resistance genes in

Tony Rochegüe, Sandrine Hughes, Estelle Saras, Benjamin Gillet, Antoine Drapeau, Philippe Glaser, Jean-Yves Madec, Marisa Haenni, Agnese Lupo

Abstract read
In one paragraph

Article in Microbial genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tony RochegüeANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
Sandrine HughesInstitut de Génomique Fonctionnelle de Lyon (IGFL), CNRS UMR 5242, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Estelle SarasANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
Benjamin GilletInstitut de Génomique Fonctionnelle de Lyon (IGFL), CNRS UMR 5242, Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Antoine DrapeauANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
Philippe GlaserEcology and Evolution of Antibiotic Resistance Unit, Institut Pasteur, Université Paris-Cité, CNRS UMR6047, Paris, France.
Jean-Yves MadecANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
Marisa HaenniANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
Agnese LupoANSES - Université de Lyon, Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In streptococci, the acquisition of high-level gentamicin resistance (HLGR) abolishes the synergy with beta-lactams, constituting a medical concern for humans and animals. This synergy between gentamicin and beta-lactams is useful to treat severe infections like endocarditis, among others. HLGR has been characterized mostly in roup B Streptococci mediated by the bi-functional gene

Indexed as

Drug Resistance, BacterialGentamicinsStreptococcal InfectionsStreptococcusAnimalsAnti-Bacterial AgentsConjugation, GeneticDNA Transposable ElementsFemaleHorse DiseasesHorsesAnti-Bacterial AgentsDNA Transposable ElementsGentamicinsaac(6′)-Imaph(2″)-IbICEEr0106Streptococcus dysgalactiae subsp. equisimilis (SDSE)Tn5252TnGBS-2

Identifiers

PMID42200513
PMCPMC13214566

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.