Evidence map›Paper›PMID 42200362›Full record

Trial reportMedical education online2026

AI-assisted case-based learning and flipped classroom to improve clinical decision-making: a randomized controlled trial in reproductive medicine.

Qi Wang, Cong Hu, Yiyang Li, Ting Zhang, Songling Zhang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical education online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi WangPrenatal Diagnosis Center, Reproductive Medicine Center, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.ORCID 0009-0006-4501-3130
Cong HuPrenatal Diagnosis Center, Reproductive Medicine Center, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.
Yiyang LiObstetrics and Gynecology Center, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.
Ting ZhangPrenatal Diagnosis Center, Reproductive Medicine Center, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.
Songling ZhangObstetrics and Gynecology Center, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEfficient training of reproductive medicine clinicians is critical in the context of declining global fertility and increasing infertility. Traditional lecture‑based instruction often fails to sufficiently develop clinical decision‑making skills within limited residency rotations. Innovative strategies that integrate artificial intelligence (AI) with case‑based learning (CBL) and flipped classroom (FC) formats may enhance clinical reasoning, however rigorous evidence in reproductive medicine education remains limited.

methodsWe conducted a randomized controlled trial involving 50 obstetrics and gynecology residents at the First Hospital of Jilin University. Participants were randomly assigned to an AI‑assisted CBL+FC group or a traditional lecture control group. The AI‑assisted CBL+FC group completed pre‑class interactive case work with virtual standardized patients on the DoctorU platform and case analyses on the Superstar Learning platform, followed by interactive in‑class discussions. Primary outcomes included post‑course theoretical knowledge tests, Mini‑Clinical Evaluation Exercise (Mini‑CEX), and Objective Structured Clinical Examination (OSCE) scores. Secondary outcomes assessed learner motivation, clinical thinking, self‑directed learning, and perceived course effectiveness using a 5‑point Likert scale.

resultsBaseline characteristics were comparable between groups. After the intervention, the AI‑assisted CBL+FC group achieved significantly higher theoretical test scores than the control group. The AI‑assisted CBL+FC group also demonstrated superior overall clinical competence in Mini‑CEX assessments and higher OSCE total scores. Participants in the AI‑assisted CBL+FC group reported greater improvements in learning motivation, clinical reasoning, self‑directed learning, and perceived course effectiveness.

conclusionsThe AI‑assisted CBL+FC instructional model significantly enhances theoretical knowledge, clinical decision‑making skills, and learner engagement among reproductive medicine residents. This blended learning model offers an efficacious and generalizable methodology for training practitioners to address the evolving clinical requirements within contemporary fertility care.

Indexed as

Artificial IntelligenceClinical Decision-MakingProblem-Based LearningReproductive MedicineAdultClinical CompetenceFemaleGynecologyHumansInternship and ResidencyObstetricsartificial intelligenceAssisted reproductive medicinecase-based learningclinical decision-makingflipped classroomresident training

Identifiers

PMID42200362
PMCPMC13218306

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.