Evidence map›Paper›PMID 42200202›Full record

ArticleFrontiers in genetics2026

Comprehensive genomic profiling of neuroendocrine neoplasms of the colorectum.

Hongfa Xu, Xiaoqin Jin, Man Chen, Shaoxiu Yang, Guanghong He, Lirong Ou, Tuhua Li, Qilian Liang, De Cai

Abstract read
In one paragraph

Article in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongfa Xu *Department of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Xiaoqin Jin *Department of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Man Chen *Department of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Shaoxiu YangDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Guanghong HeDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Lirong OuDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Tuhua LiDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Qilian LiangDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
De CaiDepartment of Clinical Pharmacy, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) are classified into G1, G2, and G3, corresponding to low-grade, intermediate-grade, and high-grade tumors, higher grades show greater aggressiveness and poorer outcomes, with molecular mechanisms remaining unclear. This study aimed to investigate gene mutations across G1, G2, and G3 in 24 colorectal neuroendocrine tumors (CRNETs) using whole-exome sequencing to identify somatic single nucleotide polymorphisms (SNPs). The results showed a prominent T>C single nucleotide variant (SNV) in G1 samples, while C>T was prevalent in G2 and G3. The analysis of significant mutated genes revealed that

Indexed as

colorectalcomprehensive genomicevolveneuroendocrine tumorssomatic mutation

Identifiers

PMID42200202
PMCPMC13200827

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