Evidence map›Paper›PMID 42200106›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026

First Comprehensive Global Bibliometric Analysis of Monkeypox Virus Research Landscape From 1976 to 2025.

Uwem Okon Edet, Md Zulfekar Ali, Bassey Ini Ubi, Edema Enogiomwan Imalele, Bassey Edet, Francisca Nwaokorie, Clement Meseko

Abstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. First Comprehensive Global Bibliometric Analysis of Monkeypox Virus Research Landscape From 1976 to 2025.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Uwem Okon EdetInfectious & Transboundary Animal Diseases, National Veterinary Research Institute (NVRI), Vom, 930101, Nigeria, nvri.gov.ng.ORCID https://orcid.org/0000-0003-0744-8564
Md Zulfekar AliAnimal Health Research Division, Bangladesh Livestock Research Institute, Savar, Dhaka, 1341, Bangladesh, blri.gov.bd.ORCID https://orcid.org/0000-0002-3971-8699
Bassey Ini UbiDepartment of Microbiology, Faculty of Biological Sciences, University of Calabar, Calabar, Cross River, Nigeria, unical.edu.ng.ORCID https://orcid.org/0000-0002-7087-1552
Edema Enogiomwan ImaleleDepartment of Zoology and Environmental Biology, Faculty of Biological Sciences, University of Calabar, Calabar, PMB1115, Cross River, Nigeria, unical.edu.ng.ORCID https://orcid.org/0000-0003-3774-5121
Bassey EdetDepartment of Biological Science (Microbiology Unit), Arthur Jarvis University, Akpabuyo, Nigeria.ORCID https://orcid.org/0000-0002-0926-0808
Francisca NwaokorieDepartment of Medical Laboratory Science, College of Medicine, University of Lagos, Lagos, Nigeria, unilag.edu.ng.ORCID https://orcid.org/0000-0003-4600-478X
Clement MesekoInfectious & Transboundary Animal Diseases, National Veterinary Research Institute (NVRI), Vom, 930101, Nigeria, nvri.gov.ng.ORCID https://orcid.org/0000-0001-7003-7528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Six decades have elapsed since the index case of monkeypox virus (MPXV) was reported. Unlike most DNA viruses characterized by slow mutation and spread, MPXV caused the global outbreak of 2022, and as expected, several studies prior and post the 2022 outbreak have emanated. Despite its ability to trigger a potential pandemic, there is no holistic quantitative and qualitative insight into MPXV research landscape globally. Methods: Following the Scientific Procedures and Rationales for Systematic Literature Review (SPAR-4-SLR protocol) applied to the Scopus database, studies were retrieved covering 1976-2025 on MPXV globally and screened using predefined criteria. The final dataset was analyzed using Biblioshiny, RStudio, and VOSviewer tool. Results: Of the 8460 retrieved records, 5315 met the inclusion and exclusion criteria, comprising 79.98% original articles and 20.02% review articles, authored by 32,098 researchers across 1547 journals. Our analysis of the MPXV research revealed an average annual growth rate of 12.38%, with a pronounced surge after 2021, coinciding with the global 2022 outbreak. The United States dominated research output, authorship, funding, institutional leadership, and international collaborations, with the Centers for Disease Control (CDC) emerging as the most influential institution. China, India, and the United Kingdom also contributed substantially, while resource-poor settings were underrepresented. Keyword and thematic analyses revealed a transition from early virological and animal studies to recent emphasis on human transmission, epidemiology, vaccination, and therapeutics. Highly cited studies were concentrated in leading infectious disease journals. Overall, MPXV research has evolved rapidly, highlighting expanding global collaboration and shifting research priorities. Conclusion: The study demonstrates a sharp post-2021 expansion of MPXV research, dominated by high-income countries, particularly the United States. Strengthening research contributions, surveillance, and collaborations from MPXV-endemic regions in Africa is essential for balanced global preparedness and response efforts.

Indexed as

bibliometric analysisemerging infectious diseasesglobal collaborationmonkeypox virusresearch trends

Identifiers

PMID42200106
PMCPMC13199685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.