Evidence map›Paper›PMID 42200081›Full record

ArticleFrontiers in medicine2026

Two-year outcomes of modified external suture trabeculotomy for Chinese open-angle glaucoma patients.

Zhan Xie, Yangyang Lu, Haiyue Xie, Zhengtong Xu, Mulong Du, Ying-Ting Zhu, Ping Xie, Hong Sun

Abstract read
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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Zhan Xie *Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
Yangyang Lu *Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
Haiyue Xie *Department of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
Zhengtong XuNanjing Qixia District Hospital, Nanjing, China.
Mulong DuDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.
Ying-Ting ZhuR&D Department, BioTissue, Miami, FL, United States.
Ping XieDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.
Hong SunDepartment of Ophthalmology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to evaluate the 2-year outcomes of modified external suture trabeculotomy in the treatment of open-angle glaucoma (OAG) among Chinese patients. Methods: A retrospective study was designed, involving 138 OAG patients (138 eyes) treated with modified external suture trabeculotomy at the First Affiliated Hospital of Nanjing Medical University from January 2020 to June 2023. The patients were followed up at 1 week, 1 month, 3 months, 6 months, 1 year, and 2 years. Surgical success was defined as intraocular pressure (IOP) ≤ 21 mmHg (1 mmHg = 0.133 kPa) under glaucoma medication (conditional success) and without any glaucoma medication (complete success). The main outcomes were measured according to IOP, number of medication regimens, surgical success rate, and complications. Results: A total of 138 OAG patients (138 eyes) were included, with a mean age of 58.57 ± 13.66 years (range, 25-86 years). The mean postoperative IOP decreased from preoperative 24.59 ± 9.82 to postoperative 15.50 ± 6.49, 15.70 ± 5.76, 14.36 ± 3.59, 14.49 ± 3.96, 14.71 ± 4.31, and 14.31 ± 3.16 mm Hg at 1 week, 1 month, 3 months, 6 months, 1 year, and 2 years, respectively. The mean numbers of medication regimens were 2 (0 ~ 4), 0 (0 ~ 3), 0 (0 ~ 3), 0 (0 ~ 3), 0 (0 ~ 2), 0 (0 ~ 3), 0 (0 ~ 3) at the seven time points, respectively. The mean postoperative IOP and the number of medication regimens at each time point were significantly lower than those before the operation (all Conclusion: Simple and cost-effective, the modified external suture trabeculotomy provides favorable 2-year outcomes in treating medically uncontrolled OAG, as shown by short surgical duration, effective IOP control, significant drug reduction, and fewer postoperative interventions.

Indexed as

2-year outcomeIOPmodified external suture trabeculotomyopen-angle glaucomaSchlemm’s canal

Identifiers

PMID42200081
PMCPMC13199026

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