Assessment of the relationship between CT-severity scores, pulmonary artery diameters, and D-dimer/CRP ratios in COVID-19 patients.

Objectives: Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, remains a global health concern. The computed tomography (CT) severity score is widely used as an objective measure of pulmonary involvement, while increased pulmonary artery (PA) diameter has emerged as a potential marker of disease severity. This study aimed to investigate the relationship between CT severity scores, PA diameter, and the D-dimer/CRP ratio, and to determine whether these parameters are independently associated with radiological severity. Materials and methods: This retrospective case-control study included 199 PCR-confirmed COVID-19 patients who underwent chest CT and laboratory evaluation. Sociodemographic and clinical data were obtained from hospital records. Laboratory parameters, including procalcitonin, C-reactive protein (CRP), D-dimer, and the D-dimer/CRP ratio, along with CT findings such as PA diameter, were analyzed. Patients were categorized according to CT severity score (0-25). Multivariable linear regression analysis was performed to identify independent predictors of CT severity. Results: Higher CT severity scores were significantly associated with increased levels of inflammatory and laboratory markers, including procalcitonin, CRP, D-dimer, and troponin (all Conclusion: Higher CT severity scores are associated with increased PA diameter and lower D-dimer/CRP ratios. Integrating radiological parameters with inflammatory markers may improve early risk stratification in COVID-19 patients.