Evidence map›Paper›PMID 42199989›Full record

ReviewOncology reviews2026

Recent advancements in the application of artificial intelligence-based approaches for screening, diagnosis, prognosis and treatment of cervical cancer.

SubbaRao V Tulimilli, Medha Karnik, Sam Cockroft, Anjali Devi S Bettadapura, Suma M Nataraj, Habeeb Shaik Mohideen, Sinisa Dovat, Arati Sharma, SubbaRao V Madhunapantula

Abstract readReview
In one paragraph

Review in Oncology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

SubbaRao V TulimilliCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory (A DST-FIST Supported Center and ICMR-Collaborating Center of Excellence), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research (JSS AHER), Mysuru, Karnataka, India.
Medha KarnikCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory (A DST-FIST Supported Center and ICMR-Collaborating Center of Excellence), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research (JSS AHER), Mysuru, Karnataka, India.
Sam CockroftDepartment of Molecular and Precision Medicine (SC, AS), Department of Pediatrics (SD), Center for Cannabis and Natural Product Pharmaceuticals (CCNPP) (AS), Penn State Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA, United States.
Anjali Devi S BettadapuraCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory (A DST-FIST Supported Center and ICMR-Collaborating Center of Excellence), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research (JSS AHER), Mysuru, Karnataka, India.
Suma M NatarajCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory (A DST-FIST Supported Center and ICMR-Collaborating Center of Excellence), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research (JSS AHER), Mysuru, Karnataka, India.
Habeeb Shaik MohideenBioinformatics and Integrative Omics Laboratory, Department of Genetic Engineering, School of Bioengineering, College of Engineering and Technology, SRM Institute of Science and Technology (formerly SRM University) Kattankulathur, Chengalpattu, India.
Sinisa DovatDepartment of Molecular and Precision Medicine (SC, AS), Department of Pediatrics (SD), Center for Cannabis and Natural Product Pharmaceuticals (CCNPP) (AS), Penn State Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA, United States.
Arati SharmaDepartment of Molecular and Precision Medicine (SC, AS), Department of Pediatrics (SD), Center for Cannabis and Natural Product Pharmaceuticals (CCNPP) (AS), Penn State Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA, United States.
SubbaRao V MadhunapantulaCenter of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory (A DST-FIST Supported Center and ICMR-Collaborating Center of Excellence), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research (JSS AHER), Mysuru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is the fourth most common type of cancer among women. Majority of CC cases (84%-90%) have been reported in low- and middle-income countries (LMICs). Persistent infection with high-risk human papilloma virus (HR-HPV) subtypes is responsible for >90% of the cervical cancers. CC is preventable by timely vaccination with HPV vaccine. Early diagnosis, treatment and disease recurrence prediction markers play a significant role in improving the patient outcome, yet LMICs are seeing a continuous increase in CC cases. Lack of sensitive self-screening technologies, effective diagnostic methods and accessible treatment options are predominantly contributing to this increase. Recent advances in artificial intelligence (AI), particularly machine learning (ML) and deep learning (DL) methods have revolutionized CC diagnosis, prognosis, and treatment agent selection by (a) enhancing the accuracy of screening and diagnostic methods; (b) assisting the clinicians in predicting various prognostic factors such as lymph node metastasis, treatment response, survival outcome, postoperative risk factors; and (c) providing dose prediction, treatment planning, segmentation of target volume and organ at risk. AI algorithms can analyze complex datasets, including medical images, patient data, and genetic information, to identify patterns and predict outcomes that might have not been considered by traditional methods. AI-based analysis provides more accurate diagnosis and improved risk stratification in a very short duration, while helping in the design of tailored treatment strategies. In this article, we aim to provide an overview of emerging ML and DL methods and comprehensively evaluate the role of AI-based approaches in the screening, diagnosis, prognosis and treatment of CC. Finally, we discuss challenges and limitations associated with the use of AI models in CC screening, diagnosis, prognosis and treatment. We have also focused on emerging AI models that can be applied in CC research and treatment to overcome the current challenges and limitations.

Indexed as

artificial intelligencecervical cancerdeep learningdiagnosismachine learningprognosisscreeningtreatment

Identifiers

PMID42199989
PMCPMC13199244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.