Evidence map›Paper›PMID 42199919›Full record

ArticleInternational journal of cardiology. Congenital heart disease2026

Surgical management of adults with congenital heart disease in Serbia: A pilot model.

Alessandro Giamberti, Federica Caldaroni, Giulia Guglielmi, Stefan Veljkovic, Ana Perunicic, Margarita Brida, Massimo Chessa, Aleksandra Nikolic

Abstract read
In one paragraph

Article in International journal of cardiology. Congenital heart disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Alessandro GiambertiPaediatric and Adult Congenital Cardiothoracic Centre, IRCCS Policlinico San Donato, San Donato M.se, Mi, Italy.
Federica CaldaroniDepartment of Cardiothoracic Surgery, The Royal Melbourne Hospital, Melbourne, Australia.
Giulia GuglielmiPaediatric and Adult Congenital Heart Disease Centre, IRCCS Policlinico San Donato, San Donato M.se, Mi, Italy.
Stefan VeljkovicInstitute for Cardiovascular Disease Dedinje, ACHD Unit, Belgrade, Serbia.
Ana PerunicicInstitute for Cardiovascular Disease Dedinje, ACHD Unit, Belgrade, Serbia.
Margarita BridaDepartment of Medical Rehabilitation, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
Massimo ChessaVita Salute San Raffaele University, Milan, Italy.
Aleksandra NikolicInstitute for Cardiovascular Disease Dedinje, ACHD Unit, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In 2014 a professional collaboration was established between IRCCS Policlinico San Donato, Milan, Italy (PSD) and the Institute for Cardiovascular Disease Dedinje, Belgrade, Serbia (ICDD) to support and improve the care of adult patients with congenital heart disease (ACHD) in the country. Since 2018, this collaboration has become more structured, with a specific focus on surgery for adults with complex congenital heart disease (CHD). Aim of the study was to evaluate the outcomes of this collaboration. Methods: We conducted a retrospective study on all consecutive adult patients (aged over 18 years) with CHD who underwent surgery at the Institute for Cardiovascular Disease Dedinje (ICDD) over a ten-year period, from January 2014 to December 2024. Collected data included number of cases, mean age at surgery, types of surgical procedures performed, number of previous operations, distribution of cases based on complexity, patient outcomes, and follow-up. Results: Between 2014 and 2024, a total of 244 ACHD patients underwent surgery at ICDD. Eighty-eight of these patients (88/244 = 36%) required complex procedures and were referred to the visiting PSD cardiac surgeon. Mean age at surgery was 34.8 years (±14 years). The most common diagnosis was right ventricular outflow tract (RVOT) pathology, accounting for 89% of cases. Seventy patients (80%) underwent reoperations following previous procedures. In-hospital mortality was 4.5% (4 patients). No additional deaths or reoperations occurred during a mean follow-up of 58 months (2-122 months). Conclusions: This ten-year international partnership demonstrates that high-quality ACHD surgical care can be delivered sustainably in countries with limited case volumes and expertise. By combining local access with external specialist support, the model has achieved outcomes comparable to high-volume Western European centres. Increased access to ACHD surgery in their home country and reduced financial burden suggests that this model of care may potentially serve in other countries facing similar healthcare challenges.

Indexed as

Adult with congenital heart diseaseCardiac surgeryGrown-up congenital heart disease

Identifiers

PMID42199919
PMCPMC13200079

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.