ReviewFrontiers in reproductive health2026
Research progress on non-invasive testing of endometrial receptivity.
Review in Frontiers in reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
Endometrial receptivity plays a crucial role in the process of embryo implantation and is a key factor affecting the success rate of assisted reproductive technology. Traditional ultrasound assessment of endometrial receptivity has poor accuracy. The development of endometrial receptivity array (ERA) detection technology and RNA sequencing (RNA-seq)-based molecular testing for endometrial receptivity has enabled personalized embryo transfer (pET) for some patients based on test results. However, as an invasive testing technique, this method requires abandoning embryo transfer during the examination cycle. With the advancement of molecular diagnostics and omics technologies, a series of novel detection methods have emerged. Studies on the transcriptomics, proteomics, and lipidomics of endometrial fluid can, to some extent, also reflect endometrial receptivity. This article primarily reviews the latest research progress in non-invasive RNA-seq-based endometrial receptivity testing (nirsERT).
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