Evidence map›Paper›PMID 42199831›Full record

ArticlePeerJ2026

Evaluation of dosimetric consistency between pre- and postoperative CT-guided noncoplanar template-assisted ¹²⁵I seed implantation in recurrent and metastatic thoracic tumors: a retrospective study.

Lingyun Qiu, Yucheng Li, Rong Wu, Yinan Chen, Ziguo Zhang, Wenming Zhan, Yinghao Zhang, Qiang Li, Aihong Bi, Limin Luo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lingyun QiuCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yucheng LiCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Rong WuDepartment of Breast Surgery, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.
Yinan ChenSchool of Medical Technology, Yunnan Engineering Vocational College, Yunnan, China.
Ziguo ZhangSchool of National Defence Science & Technology, Southwest University of Science and Technology, Mianyang, Sichuan, China.
Wenming ZhanCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yinghao ZhangCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Qiang LiCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Aihong BiCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Limin LuoCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Weijun ChenCancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Zhiwen YanCancer Center, Clinical Medical Engineering Department, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Recurrent and metastatic thoracic malignancies remain challenging to manage because of their proximity to vital structures and the impact of respiratory motion on dose accuracy. This retrospective study aimed to assess the dosimetric consistency between preoperative planning and postoperative verification in computed tomography (CT)-guided 3D-printed noncoplanar template (3DPNCT)-assisted ¹²⁵I seed implantation. Methods: Clinical and dosimetric data from 32 patients who underwent 3DPNCT-assisted seed implantation were retrospectively reviewed. Preoperative treatment plans were compared with postoperative dose verification to evaluate deviations in key indices, including target coverage, dose conformity, and homogeneity. Statistical comparisons were performed using appropriate paired analyses, and agreement between planned and delivered doses was further evaluated through Bland-Altman analysis. Results: The mean D90 decreased from 142.47 ± 28.90 Gy to 135.06 ± 31.66 Gy ( Conclusions: CT-guided 3DPNCT-assisted ¹²⁵I seed implantation achieves robust dosimetric reproducibility and favorable plan accuracy in thoracic tumors. Despite minor deviations related to respiratory motion and intraoperative uncertainties, this approach provides a reliable and clinically feasible option for managing complex thoracic malignancies. Further prospective studies incorporating motion management and real-time adaptive planning are warranted to optimize its clinical application.

Indexed as

BrachytherapyIodine RadioisotopesLung NeoplasmsNeoplasm Recurrence, LocalThoracic NeoplasmsTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesIodine-125Iodine RadioisotopesCT-guided brachytherapyDosimetryNoncoplanar templateRadioactive seed implantationRetrospective studyThoracic tumors

Identifiers

PMID42199831
PMCPMC13200664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.