ArticleTropical parasitology
Clinicopathological study of giardiasis: A retrospective descriptive study from a tertiary care center in South India.
Article in Tropical parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Aims: This retrospective study analyzed all biopsy-confirmed cases of giardiasis to evaluate their microscopic features. Materials and Methods: This retrospective descriptive study analyzed 30 biopsy-proven duodenal giardiasis cases. Clinical, endoscopic, and histopathological parameters were reviewed, including parasite density, villous changes, lymphoid hyperplasia, and inflammation. Slides stained with hematoxylin and eosin stain and Giemsa stain were examined microscopically. Data was analyzed using descriptive statistics and expressed as frequencies and percentages. Results: Among 30 cases studied over 12 years, diarrhea was the predominant indication for endoscopy. Endoscopic nodularity was identified in 50% of patients, with the parasite most commonly located in the first or second part of the duodenum. Moderate lamina propria inflammation was present in 77% of cases. Diffuse nodular lymphoid hyperplasia was noted in 11 cases, including two with follicular diameters of 720 µm and 900 µm. Villous morphology varied from normal to varying degrees of flattening, blunting, and atrophy. Conclusion: Mucosal nodularity was frequently observed with moderate inflammation of lamina propria. The presence of lymphoid follicles in biopsies may serve as a soft clue. Vigilant searches for
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