ArticleCureus2026
Anticoagulation Pauses and Anesthetic Options: A Case for Multidisciplinary Harmonization.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perioperative anticoagulation management is increasingly guided by recommendations from multiple specialties, including cardiology, thrombosis medicine, stroke medicine, and surgery. These frameworks, while intending to improve standardization of interruption and resumption strategies for antithrombotic therapy, are largely centered on surgical bleeding risk and thromboembolic risk, while regional anesthesia (RA) guidelines differ in pause intervals for many oral anticoagulants due to the differing thresholds for acceptable residual anticoagulant activity, with the potentially catastrophic consequences of neuraxial hematoma in mind. Emerging evidence also suggests that measurable direct oral anticoagulant (DOAC) activity may persist despite guideline-consistent interruption in some patients, highlighting pharmacokinetic variability in real-world perioperative populations. Multidisciplinary, institution-specific frameworks and testing of anticoagulant activity in select cases may help harmonize multiple sources of guidance and support coordinated decision-making across surgical, anesthesia, and perioperative care teams. In this perspective piece, we intend to highlight discrepancies in perioperative anticoagulation guidance and discuss ways to promote harmonization strategies with considerations for RA choices.
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