Evidence map›Paper›PMID 42199536›Full record

ReviewFrontiers in gastroenterology (Lausanne, Switzerland)2026

Comparative analysis of anal sphincter-preserving surgical techniques in ultra-low rectal cancer.

Hongjun Yuan, Jun Bu, Peng Zhang

Abstract readReview
In one paragraph

Review in Frontiers in gastroenterology (Lausanne, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hongjun YuanDepartment of General Surgery, Sichuan University Affiliated Chengdu Second People's Hospital, Chengdu, China.
Jun BuDepartment of General Surgery, Sichuan University Affiliated Chengdu Second People's Hospital, Chengdu, China.
Peng ZhangDepartment of General Surgery, Sichuan University Affiliated Chengdu Second People's Hospital, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultra-low rectal cancer refers to a tumor situated very close to the anal verge, typically within 3 cm from the proximal end of the anal dentate line. Its location creates significant challenges for achieving clear surgical margins necessary to achieve local tumor control while preserving sphincter function to minimize the risk of developing fecal incontinence and other complications.This review summarizes six sphincter-preserving techniques for ultra-low rectal cancer: local excision, low anterior resection(LAR, with or without prophylactic ileostomy or ileal stent), intersphincteric resection (ISR), modified Bacon and Parks procedures, transanal total mesorectal excision (TaTME), and Natural Orifice Specimen Extraction Surgery with Precision Functional Sphincter-Preserving Surgery(NOSES-PPS). While most approaches achieve satisfactory oncological outcomes, postoperative anal function remains a major concern. Preliminary evidence suggests NOSES-PPS may offer benefits in preserving anal function, though current studies are limited by small sample sizes and lack of large-scale trials. Optimal outcomes depend on patient selection, surgical expertise, and perioperative management.

Indexed as

anal functionanal sphincter-preservingLARSlow anterior resection syndromeultra-low rectal cancer

Identifiers

PMID42199536
PMCPMC13199000

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.