Evidence map›Paper›PMID 42199515›Full record

ReviewStructural heart : the journal of the Heart Team2026

Outcomes of Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Reduced Left Ventricular Ejection Fraction: A Meta-Analysis of Observational Studies.

Qasi Najah, Sara Saleh, Mustafa Zubaidi, Howard C Herrmann, Luigi Pirelli, Rebecca T Hahn, Luis Nombela-Franco, Thomas Pilgrim, Josep Rodés-Cabau, Muhammed Elhadi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Structural heart : the journal of the Heart Team, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qasi NajahFaculty of Medicine, Elmergib University, Alkhums, Libya.
Sara SalehFaculty of Medicine, Hashemite University, Zarqa, Jordan.
Mustafa ZubaidiWasit University, College of Medicine, Wasit, Iraq.
Howard C HerrmannPerelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Luigi PirelliDivision of Cardiothoracic Surgery, New York-Presbyterian Hospital, Columbia University Medical Center, New York, New York, USA.
Rebecca T HahnCardiology Department, NewYork-Presbyterian/Columbia University Medical Center, New York, New York, USA.
Luis Nombela-FrancoCardiovascular Institute, Hospital Clínico San Carlos, IdISSC, Madrid, Spain.
Thomas PilgrimDepartment of Cardiology, Inselspital, University of Bern, Bern, Switzerland.
Josep Rodés-CabauQuebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada.
Muhammed ElhadiFaculty of Medicine, University of Tripoli, Tripoli, Libya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with reduced left ventricular ejection fraction (LVEF) undergoing transcatheter aortic valve replacement remain a clinically vulnerable group. Although self-expanding valves (SEVs) and balloon-expandable valves are widely used, the optimal choice in patients with LVEF <40% remains uncertain. We aimed to synthesize the available evidence comparing these two valve types in this high-risk population. We conducted a systematic review and meta-analysis of observational studies comparing SEVs and balloon-expandable valves in patients with LVEF <40% undergoing transcatheter aortic valve replacement. Outcomes included changes in LVEF, aortic gradients, mortality, and safety endpoints. Pooled estimates were calculated using random-effects models, and multivariable meta-regression was performed to adjust for study-level confounding. Five studies comprising 5365 patients were included. SEVs were associated with a greater improvement in 1-month LVEF (mean difference, 2.33; 95% confidence interval [CI], 0.83 to 3.83;

Indexed as

Aortic stenosisBalloon-expandable valveSelf-expandable valveSystolic dysfunctionTranscatheter aortic valve replacement

Identifiers

PMID42199515
PMCPMC13200108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.