Trial reportFrontiers in human neuroscience2026
Tai Chi alleviates pain on fusiform-lingual and rolandic operculum-insula circuit in older participants with chronic low back pain: a randomized controlled neuroimaging trial.
Trial report in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Background: Chronic low back pain (CLBP) is a common clinical syndrome and a leading cause of disability. The high disability rate associated with CLBP is more susceptible to reduced labor capacity, poorer quality of life, and increased psychological, social, and medical burdens. Tai Chi is an effective and safe therapy for treating chronic low back pain (CLBP). Objective: This study aims to determine the effect of Tai Chi on brain function in patients with CLBP. Methods: The study included 72 participants randomly divided into a Tai Chi group and a control group. The Tai Chi group received a Yang-style 24-form Tai Chi program for 8 weeks. The control group had a waiting time of 8 weeks. Participants underwent a functional magnetic resonance imaging (fMRI) scan. The study was approved by the Ethics Committee of the Hospital of Chengdu University of Traditional Chinese Medicine in Sichuan Province (No. 2022KL-038-02) and registered with the Chinese Clinical Trial Registry under the number ChiCTR2200064977. Results: The Visual Analog Score (VAS), duration and frequency of pain, Japanese Orthopaedic Association (JOA) scores, and Oswestry Disability Index (ODI) significantly improved at 8 weeks ( Conclusion: This study indicated that Tai Chi training could effectively relieve pain and improve physical function in elderly people with CLBP. The study suggested that the fusiform-lingual and rolandic operculum-insula circuits are potential treatment regions that might be the mechanism for the effect of Tai Chi. Clinical Trial Registration: https://www.chictr.org.cn, Chinese Clinical Trial Registry (ChiCTR2200064977).
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