ArticleFrontiers in cardiovascular medicine2026
Sex-related differences in conduit strategy and early outcomes after sternum-sparing on-pump multivessel CABG via left anterior thoracotomy.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Sex-related disparities after conventional coronary artery bypass grafting (CABG) have been consistently reported, including differences in baseline risk profile, conduit strategy, and early adverse events. However, data on outcomes after sternum-sparing minimally invasive multivessel CABG remain limited. This study aimed to evaluate sex-related differences in baseline characteristics, operative strategy, and in-hospital outcomes in patients undergoing minimally invasive multivessel CABG using total coronary revascularization via left anterior thoracotomy (TCRAT). Methods: From November 2019 to December 2025, CABG via left anterior minithoracotomy with cardioplegic arrest was the preferred surgical approach in our institution. The analysis included 807 men and 138 women undergoing non-emergency TCRAT. Baseline characteristics, grafting strategy, procedural times, and in-hospital outcomes, including mortality, stroke, myocardial infarction, repeat revascularization, and MACCE, were compared between sexes. Results: Women were older (69.2 ± 8.9 vs. 66.7 ± 9.4 years, Conclusion: Sternum-sparing multivessel CABG via left anterior thoracotomy was associated with similar early postoperative outcomes in men and women despite differences in baseline characteristics and conduit selection. Given the observational design and low event rates, these findings should be interpreted with appropriate caution.
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