Evidence map›Paper›PMID 42198761›Full record

ArticleViruses2026

Reassortant High Pathogenicity Avian Influenza A(H5N1) Viruses During the Reemergence in Uruguay Suggest Increasing Genetic Diversity in South America.

Ana Marandino, Gonzalo Tomás, Yanina Panzera, Valeria Uriarte, Virginia Russi, Ramiro Pérez, Lucía Bassetti, Raúl Negro, Sirley Rodríguez, Ruben Pérez

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana MarandinoSección Genética Evolutiva, Departamento de Biología Animal, Instituto de Biología, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay.
Gonzalo TomásSección Genética Evolutiva, Departamento de Biología Animal, Instituto de Biología, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay.ORCID 0000-0002-0530-2046
Yanina PanzeraSección Genética Evolutiva, Departamento de Biología Animal, Instituto de Biología, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay.ORCID 0000-0002-7459-7810
Valeria UriarteDirección Nacional de Biodiversidad y Servicios Ecosistémicos (DINABISE), Ministerio de Ambiente, Juncal 1385, Montevideo 11100, Uruguay.
Virginia RussiDivisión de Sanidad Animal, Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agricultura y Pesca, Ruta 8 "Brigadier Gral. Juan A. Lavalleja" Km 17,000, Montevideo 12100, Uruguay.
Ramiro PérezDepartamento de Virología, División de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agricultura y Pesca, Ruta 8 "Brigadier Gral. Juan A. Lavalleja" Km 17,000, Montevideo 12100, Uruguay.
Lucía BassettiDepartamento de Virología, División de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agricultura y Pesca, Ruta 8 "Brigadier Gral. Juan A. Lavalleja" Km 17,000, Montevideo 12100, Uruguay.
Raúl NegroDepartamento de Virología, División de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agricultura y Pesca, Ruta 8 "Brigadier Gral. Juan A. Lavalleja" Km 17,000, Montevideo 12100, Uruguay.
Sirley RodríguezDepartamento de Virología, División de Laboratorios Veterinarios "Miguel C. Rubino", Dirección General de Servicios Ganaderos, Ministerio de Ganadería, Agricultura y Pesca, Ruta 8 "Brigadier Gral. Juan A. Lavalleja" Km 17,000, Montevideo 12100, Uruguay.
Ruben PérezSección Genética Evolutiva, Departamento de Biología Animal, Instituto de Biología, Facultad de Ciencias, Universidad de la República, Iguá 4225, Montevideo 11400, Uruguay.ORCID 0000-0003-4961-4743

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Highly pathogenic avian influenza (HPAI) H5N1 viruses of the goose/Guangdong (Gs/GD) lineage have driven a global panzootic since 2020, with clade 2.3.4.4b establishing sustained transmission in wild birds. In South America, early outbreaks were largely associated with the North American-derived B3.2 genotype, which showed limited diversification after its introduction. Here, we report the genomic characterization of eight H5N1 viruses detected in Uruguay during the reemergence of avian influenza in February-March 2026. Complete genomes were obtained from wild birds exhibiting neurological signs, predominantly

Indexed as

Genetic VariationInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsReassortant VirusesAnimalsAnimals, WildBirdsGenome, ViralGenotypePhylogenyUruguayavian influenzagenomic surveillanceH5N1phylogeneticsreassortmentRT-qPCRSouth Americaviral evolution

Identifiers

PMID42198761
PMCPMC13211659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.