Evidence map›Paper›PMID 42198729›Full record

ArticleViruses2026

Isolation of Bacteriophages with Lytic Activity from Biological Samples of Left Ventricular Assist Device Patients: An In Vitro Study.

Balazs Sax, Adam Koppanyi, Katalin Kristof, Akos Kiraly, Gyula Prinz, Istvan Hartyanszky, Gergely Gyorgy Nagy, Istvan Nemet, Fanni Temesvari-Kis, Balazs Kiss and 1 more

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Balazs SaxHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-6829-0548
Adam KoppanyiHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.
Katalin KristofInstitute of Laboratory Medicine, Semmelweis University, 1085 Budapest, Hungary.
Akos KiralyHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.ORCID 0009-0001-0717-3663
Gyula PrinzHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.
Istvan HartyanszkyHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.
Gergely Gyorgy NagyCentre for Cardiovascular Diseases and Internal Medicine, Borsod-Abauj-Zemplen County Central Hospital and University Teaching Hospital, 3526 Miskolc, Hungary.ORCID 0000-0002-0826-4700
Istvan NemetFluart Innovative Vaccines Ltd., 2097 Pilisborosjeno, Hungary.
Fanni Temesvari-KisFluart Innovative Vaccines Ltd., 2097 Pilisborosjeno, Hungary.
Balazs KissFluart Innovative Vaccines Ltd., 2097 Pilisborosjeno, Hungary.ORCID 0000-0003-3161-4518
Bela MerkelyHeart and Vascular Center, Semmelweis University, 1085 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous cable infection of left ventricular assist device (LVAD) patients is a significant source of morbidity, often caused by biofilm-producing or multidrug-resistant bacteria. We hypothesized that bacteriophage viruses can be identified from biological samples of patients with active driveline infection. Six patients with local percutaneous lead infections were enrolled. Microbiological samples were collected from the infected wound and other skin regions. The isolated viral strains and phages from wastewater samples were then tested against the pathogen bacterial cultures in vitro. Biofilm disruption assay and genetic analysis of the strains were also performed. Bacteriophages with lytic activity could be identified from samples of two patients. One patient contained four strains showing strong efficacy against his own

Indexed as

BacteriophagesHeart-Assist DevicesBiofilmsHumansLysogenyMaleStaphylococcus epidermidisWastewaterWastewaterbacteriophagesbiofilmsdriveline infectionleft ventricular assist devicephage therapy

Identifiers

PMID42198729
PMCPMC13211684

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.