ReviewViruses2026
Co-Feeding Transmission of Tick-Borne Viruses.
Review in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Tick-borne viruses (TBVs) are a diverse group of arthropod-borne pathogens maintained in complex transmission cycles involving both tick vectors and vertebrate hosts. Among the known TBV transmission routes, co-feeding transmission, in which virus is transferred from an infected tick to an uninfected tick feeding on the same vertebrate host even in the absence of a detectable viremia, represents an important route that contributes to viral maintenance in nature. Although co-feeding transmission has been demonstrated across multiple vector, host, and virus combinations, the mechanisms governing this transmission route remain poorly defined. This review synthesizes current understanding of co-feeding transmission and highlights the importance of ecological and immunological factors that shape this process in nature. Specifically, we emphasize the role of the cutaneous microenvironment at the tick co-feeding site, where localized viral replication and tick salivary factors create conditions favorable for virus transfer between co-feeding ticks. We also highlight the requirements for co-feeding transmission to occur in nature and across seasons. Together, these insights support a model in which localized skin infection is a central feature of co-feeding transmission while underscoring key gaps in our understanding of the cellular and molecular mechanisms that govern this process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.