Evidence map›Paper›PMID 42198710›Full record

ArticleViruses2026

The Value of Hepatitis E Screening Sensitivity: Lookback Investigation in German Blood Donors.

Ricarda Plümers, Jens Dreier, Attila Mandl, Cornelius Knabbe, Tanja Vollmer

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ricarda PlümersInstitute for Laboratory and Transfusion medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.ORCID 0000-0003-2265-9415
Jens DreierInstitute for Laboratory and Transfusion medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.ORCID 0000-0002-1337-7750
Attila MandlInstitute for Laboratory and Transfusion medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.ORCID 0009-0003-6302-4894
Cornelius KnabbeInstitute for Laboratory and Transfusion medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.
Tanja VollmerInstitute for Laboratory and Transfusion medicine, Heart and Diabetes Center North Rhine Westphalia, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt FKZ 01EK2106A
6 · The paper itself

Abstract

Hepatitis E virus (HEV) is the leading cause of hepatitis globally and poses particular risks for immunocompromised individuals. Mandatory screening of blood donations for HEV RNA and retrospective individual testing of previous donations (lookback investigations) following a reactive result have been implemented in several countries to protect these patients. This includes Germany, where a sensitivity limit of 2000 IU/mL applies to index donations. In total, 334 HEV RNA-positive blood donations were detected at our blood donation service between 2018 and 2024. Lookback testing was applied in 211 cases, revealing previous HEV RNA-positive donations in 23.1% of donors (

Indexed as

Blood DonorsHepatitis EHepatitis E virusMass ScreeningAdultFemaleGermanyHumansMaleRetrospective StudiesRNA, ViralSensitivity and SpecificityViral LoadRNA, Viralblood safetyhepatitis E viruslookbacktransfusion-transmitted infections

Identifiers

PMID42198710
PMCPMC13211695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.